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Extracellular vesicles derived from umbilical cord mesenchymal stromal cells alleviate pulmonary fibrosis by means of transforming growth factor-β signaling inhibition

BACKGROUND: Pulmonary fibrosis (PF), the end point of interstitial lung diseases, is characterized by myofibroblast over differentiation and excessive extracellular matrix accumulation, leading to progressive organ dysfunction and usually a terminal outcome. Studies have shown that umbilical cord-de...

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Detalles Bibliográficos
Autores principales:	Shi, Liyan, Ren, Jing, Li, Jiping, Wang, Dongxu, Wang, Yusu, Qin, Tao, Li, Xiuying, Zhang, Guokun, Li, Chunyi, Wang, Yimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041243/ https://www.ncbi.nlm.nih.gov/pubmed/33845892 http://dx.doi.org/10.1186/s13287-021-02296-8

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