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Enantioselective α-Arylation of Ketones via a Novel Cu(I)–Bis(phosphine) Dioxide Catalytic System

[Image: see text] A novel catalytic system based on copper(I) and chiral bis(phosphine) dioxides is described. This allows the arylation of silyl enol ethers to access enolizable α-arylated ketones in good yields and enantiomeric excess up to 95%. Noncyclic ketones are amenable substrates with this...

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Detalles Bibliográficos
Autores principales:	Escudero-Casao, Margarita, Licini, Giulia, Orlandi, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041290/ https://www.ncbi.nlm.nih.gov/pubmed/33635068 http://dx.doi.org/10.1021/jacs.0c13236

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