Cargando…
Tuning the Thermoresponsive Behavior of Surface-Attached PNIPAM Networks: Varying the Crosslinker Content in SI-ATRP
[Image: see text] The synthesis and thermoresponsive properties of surface-attached poly(N-isopropylacrylamide)-co-N,N′-methylene bisacrylamide (PNIPAM-co-MBAM) networks are investigated. The networks are formed via SI-ARGET-ATRP (“grafting-from”) on thiol-based initiator-functionalized gold films....
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041372/ https://www.ncbi.nlm.nih.gov/pubmed/33719454 http://dx.doi.org/10.1021/acs.langmuir.0c03545 |
_version_ | 1783677924889591808 |
---|---|
author | Thiele, Sophia Andersson, John Dahlin, Andreas Hailes, Rebekah L. N. |
author_facet | Thiele, Sophia Andersson, John Dahlin, Andreas Hailes, Rebekah L. N. |
author_sort | Thiele, Sophia |
collection | PubMed |
description | [Image: see text] The synthesis and thermoresponsive properties of surface-attached poly(N-isopropylacrylamide)-co-N,N′-methylene bisacrylamide (PNIPAM-co-MBAM) networks are investigated. The networks are formed via SI-ARGET-ATRP (“grafting-from”) on thiol-based initiator-functionalized gold films. This method is reliable, well controlled, fast, and applicable to patterned surfaces (e.g., nanopores) for networks with dry thicknesses >20 nm. Surface-attached PNIPAM-co-MBAM gels are swollen below their volume phase transition temperature but above collapse without complete expulsion of water (retain ∼50 vol %). The swelling/collapse transition is studied using complementary SPR and QCMD techniques. The ratio between swollen and collapsed heights characterizes the thermoresponsive behavior and is shown to not depend on network height but to vary with MBAM content. The higher the proportion of the crosslinker, the lower the magnitude of the phase transition, until all responsiveness is lost at 5 mol % MBAM. The temperature range of the transition is broadened for more crosslinked PNIPAM-co-MBAM gels but remains centered around 32 °C. Upon reswelling, less crosslinked networks display sharp transitions, while for those containing ≥3 mol % MBAM, transitions remain broad. This tunable behavior persists for gels on nanostructured gold surfaces. Investigating PNIPAM-co-MBAM networks on gold plasmonic nanowell arrays is a starting point for expanding their scope as thermo-controlled nanoactuators. |
format | Online Article Text |
id | pubmed-8041372 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | American
Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-80413722021-04-13 Tuning the Thermoresponsive Behavior of Surface-Attached PNIPAM Networks: Varying the Crosslinker Content in SI-ATRP Thiele, Sophia Andersson, John Dahlin, Andreas Hailes, Rebekah L. N. Langmuir [Image: see text] The synthesis and thermoresponsive properties of surface-attached poly(N-isopropylacrylamide)-co-N,N′-methylene bisacrylamide (PNIPAM-co-MBAM) networks are investigated. The networks are formed via SI-ARGET-ATRP (“grafting-from”) on thiol-based initiator-functionalized gold films. This method is reliable, well controlled, fast, and applicable to patterned surfaces (e.g., nanopores) for networks with dry thicknesses >20 nm. Surface-attached PNIPAM-co-MBAM gels are swollen below their volume phase transition temperature but above collapse without complete expulsion of water (retain ∼50 vol %). The swelling/collapse transition is studied using complementary SPR and QCMD techniques. The ratio between swollen and collapsed heights characterizes the thermoresponsive behavior and is shown to not depend on network height but to vary with MBAM content. The higher the proportion of the crosslinker, the lower the magnitude of the phase transition, until all responsiveness is lost at 5 mol % MBAM. The temperature range of the transition is broadened for more crosslinked PNIPAM-co-MBAM gels but remains centered around 32 °C. Upon reswelling, less crosslinked networks display sharp transitions, while for those containing ≥3 mol % MBAM, transitions remain broad. This tunable behavior persists for gels on nanostructured gold surfaces. Investigating PNIPAM-co-MBAM networks on gold plasmonic nanowell arrays is a starting point for expanding their scope as thermo-controlled nanoactuators. American Chemical Society 2021-03-15 2021-03-23 /pmc/articles/PMC8041372/ /pubmed/33719454 http://dx.doi.org/10.1021/acs.langmuir.0c03545 Text en © 2021 The Authors. Published by American Chemical Society Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Thiele, Sophia Andersson, John Dahlin, Andreas Hailes, Rebekah L. N. Tuning the Thermoresponsive Behavior of Surface-Attached PNIPAM Networks: Varying the Crosslinker Content in SI-ATRP |
title | Tuning the Thermoresponsive Behavior of Surface-Attached
PNIPAM Networks: Varying the Crosslinker Content in SI-ATRP |
title_full | Tuning the Thermoresponsive Behavior of Surface-Attached
PNIPAM Networks: Varying the Crosslinker Content in SI-ATRP |
title_fullStr | Tuning the Thermoresponsive Behavior of Surface-Attached
PNIPAM Networks: Varying the Crosslinker Content in SI-ATRP |
title_full_unstemmed | Tuning the Thermoresponsive Behavior of Surface-Attached
PNIPAM Networks: Varying the Crosslinker Content in SI-ATRP |
title_short | Tuning the Thermoresponsive Behavior of Surface-Attached
PNIPAM Networks: Varying the Crosslinker Content in SI-ATRP |
title_sort | tuning the thermoresponsive behavior of surface-attached
pnipam networks: varying the crosslinker content in si-atrp |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041372/ https://www.ncbi.nlm.nih.gov/pubmed/33719454 http://dx.doi.org/10.1021/acs.langmuir.0c03545 |
work_keys_str_mv | AT thielesophia tuningthethermoresponsivebehaviorofsurfaceattachedpnipamnetworksvaryingthecrosslinkercontentinsiatrp AT anderssonjohn tuningthethermoresponsivebehaviorofsurfaceattachedpnipamnetworksvaryingthecrosslinkercontentinsiatrp AT dahlinandreas tuningthethermoresponsivebehaviorofsurfaceattachedpnipamnetworksvaryingthecrosslinkercontentinsiatrp AT hailesrebekahln tuningthethermoresponsivebehaviorofsurfaceattachedpnipamnetworksvaryingthecrosslinkercontentinsiatrp |