Cargando…

Natural Dietary Supplement, Carvacrol, Alleviates LPS-Induced Oxidative Stress, Neurodegeneration, and Depressive-Like Behaviors via the Nrf2/HO-1 Pathway

PURPOSE: Major depressive disorder (MDD) is a debilitating human health condition characterized by mood swings and is associated with a high probability of suicide attempts. Several studies have reported a role of neuroinflammation in MMD, yet the efficacy of natural drug substances on neuroinflamma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Naeem, Komal, Tariq Al Kury, Lina, Nasar, Faiza, Alattar, Abdullah, Alshaman, Reem, Shah, Fawad Ali, Khan, Arif-ullah, Li, Shupeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041651/ https://www.ncbi.nlm.nih.gov/pubmed/33854358 http://dx.doi.org/10.2147/JIR.S294413

Ejemplares similares

Carvacrol Alleviates Hyperuricemia-Induced Oxidative Stress and Inflammation by Modulating the NLRP3/NF-κB Pathwayt
por: Riaz, Muhammad, et al.
Publicado: (2022)

Potent Natural Antioxidant Carveol Attenuates MCAO-Stress Induced Oxidative, Neurodegeneration by Regulating the Nrf-2 Pathway
por: Malik, Imran, et al.
Publicado: (2020)

Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole-Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway
por: Alvi, Arooj Mohsin, et al.
Publicado: (2021)

Natural Dietary Supplement, Carvacrol, Alleviates LPS-Induced Oxidative Stress, Neurodegeneration, and Depressive-Like Behaviors via the Nrf2/HO-1 Pathway [Retraction]
Publicado: (2022)

Ibrutinib attenuated DSS-induced ulcerative colitis, oxidative stress, and the inflammatory cascade by modulating the PI3K/Akt and JNK/NF-κB pathways
por: Hao, Liangliang, et al.
Publicado: (2022)

Carveol a Naturally-Derived Potent and Emerging Nrf2 Activator Protects Against Acetaminophen-Induced Hepatotoxicity
por: Rahman, Zaif Ur, et al.
Publicado: (2021)

Benzimidazole Containing Acetamide Derivatives Attenuate Neuroinflammation and Oxidative Stress in Ethanol-Induced Neurodegeneration
por: Imran, Muhammad, et al.
Publicado: (2020)

Ginkgo biloba Extract Protects against Methotrexate-Induced Hepatotoxicity: A Computational and Pharmacological Approach
por: Al Kury, Lina Tariq, et al.
Publicado: (2020)

A Potent Antioxidant Endogenous Neurohormone Melatonin, Rescued MCAO by Attenuating Oxidative Stress-Associated Neuroinflammation
por: Ling, Li, et al.
Publicado: (2020)

Post-Treatment of Synthetic Polyphenolic 1,3,4 Oxadiazole Compound A3, Attenuated Ischemic Stroke-Induced Neuroinflammation and Neurodegeneration
por: Mohsin Alvi, Arooj, et al.
Publicado: (2020)

Synthesis, In Silico and Pharmacological Evaluation of New Thiazolidine-4-Carboxylic Acid Derivatives Against Ethanol-Induced Neurodegeneration and Memory Impairment
por: Naz, Shagufta, et al.
Publicado: (2022)

Succinamide Derivatives Ameliorate Neuroinflammation and Oxidative Stress in Scopolamine-Induced Neurodegeneration
por: Iqbal, Sumbal, et al.
Publicado: (2020)

Opioids Alleviate Oxidative Stress via the Nrf2/HO-1 Pathway in LPS-Stimulated Microglia
por: Shivling Mali, Akash, et al.
Publicado: (2023)

Carveol Promotes Nrf2 Contribution in Depressive Disorders through an Anti-inflammatory Mechanism
por: Muhammad, Asmaa Jan, et al.
Publicado: (2022)

Benzimidazole Derivatives as New Potential NLRP3 Inflammasome Inhibitors That Provide Neuroprotection in a Rodent Model of Neurodegeneration and Memory Impairment
por: Ullah, Aman, et al.
Publicado: (2022)

Melatonin Act as an Antidepressant via Attenuation of Neuroinflammation by Targeting Sirt1/Nrf2/HO-1 Signaling
por: Ali, Tahir, et al.
Publicado: (2020)

Tetrahydropyrimidines, ZL-5015 Alleviated Lipopolysaccharide (LPS)-Induced Acute Pneumonia in Rats by Activating the NRF-2/HO-1 Pathway
por: Sun, Wei, et al.
Publicado: (2020)

Quercetin Alleviated Inflammasome-Mediated Pyroptosis and Modulated the mTOR/P70S6/P6/eIF4E/4EBP1 Pathway in Ischemic Stroke
por: Alattar, Abdullah, et al.
Publicado: (2023)

Neuroprotective effects of melatonin and celecoxib against ethanol-induced neurodegeneration: a computational and pharmacological approach
por: Al Kury, Lina T, et al.
Publicado: (2019)

NF-κB Inhibitors Attenuate MCAO Induced Neurodegeneration and Oxidative Stress—A Reprofiling Approach
por: Ali, Awais, et al.
Publicado: (2020)

Therapeutic effects of sulforaphane in ulcerative colitis: effect on antioxidant activity, mitochondrial biogenesis and DNA polymerization
por: Alattar, Abdullah, et al.
Publicado: (2022)

Botanical formulation, TADIOS, alleviates lipopolysaccharide (LPS)-Induced acute lung injury in mice via modulation of the Nrf2-HO-1 signaling pathway
por: Lee, Wonwoo, et al.
Publicado: (2021)

Baicalin Alleviates LPS-Induced Oxidative Stress via NF-κB and Nrf2–HO1 Signaling Pathways in IPEC-J2 Cells
por: Bao, Minglong, et al.
Publicado: (2022)

Computational and Pharmacological Evaluation of Carveol for Antidiabetic Potential
por: Ahmed, Muhammad Shabir, et al.
Publicado: (2020)

Targeted activation of Nrf2/HO‐1 pathway by Corynoline alleviates osteoporosis development
por: Xu, Tian‐hao, et al.
Publicado: (2023)

Thiazolidine Derivatives Attenuate Carrageenan-Induced Inflammatory Pain in Mice
por: Malik, Zulkifal, et al.
Publicado: (2021)

Procyanidin A1 Alleviates Inflammatory Response induced by LPS through NF-κB, MAPK, and Nrf2/HO-1 Pathways in RAW264.7 cells
por: Han, Shan, et al.
Publicado: (2019)

Dihydroquercetin Activates AMPK/Nrf2/HO-1 Signaling in Macrophages and Attenuates Inflammation in LPS-Induced Endotoxemic Mice
por: Lei, Liming, et al.
Publicado: (2020)

Effect of Apremilast on LPS-induced immunomodulation and inflammation via activation of Nrf2/HO-1 pathways in rat lungs
por: Al-Harbi, Naif O., et al.
Publicado: (2023)

Carvacrol
por: Bogue, E. A.
Publicado: (1874)

Dexmedetomidine alleviates LPS-induced acute lung injury via regulation of the p38/HO-1 pathway
por: Sun, Yingying, et al.
Publicado: (2020)

Carvacrol may alleviate vascular inflammation in diabetic db/db mice
por: Zhao, Wei, et al.
Publicado: (2020)

6-Gingerol Alleviates Ferroptosis and Inflammation of Diabetic Cardiomyopathy via the Nrf2/HO-1 Pathway
por: Wu, Shenglin, et al.
Publicado: (2022)

Andrographolide alleviates paraquat-induced acute lung injury by activating the Nrf2/HO-1 pathway
por: Zhang, Degang, et al.
Publicado: (2023)

Sulforaphane alleviates lung ischemia‑reperfusion injury through activating Nrf‑2/HO‑1 signaling
por: Zhang, Liang, et al.
Publicado: (2023)

In Vivo, Proteomic, and In Silico Investigation of Sapodilla for Therapeutic Potential in Gastrointestinal Disorders
por: Ansari, Sameen Fatima, et al.
Publicado: (2019)

Proteomic Analysis and In Vivo Studies Reveal the Potential Gastroprotective Effects of CHCl(3) and Aqueous Extracts of Ficus palmata
por: Ansari, Sameen Fatima, et al.
Publicado: (2021)

Melatonin Suppresses LPS-Induced Oxidative Stress in Dendritic Cells for Inflammatory Regulation via the Nrf2/HO-1 Axis
por: Qin, Tao, et al.
Publicado: (2022)

Allicin protects against LPS-induced cardiomyocyte injury by activating Nrf2-HO-1 and inhibiting NLRP3 pathways
por: Sun, Fangyuan, et al.
Publicado: (2023)

Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models
por: He, Dewei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sp9s427b3on8f5g2h8768lm8bl