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A Matter of Timing—Pregnancy After Bariatric Surgery
PURPOSE: Current guidelines recommend to avoid pregnancy for 12–24 months after bariatric surgery because of active weight loss and an increased risk of nutritional deficiencies. However, high-quality evidence is lacking, and only a few studies included data on gestational weight gain. We therefore...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041698/ https://www.ncbi.nlm.nih.gov/pubmed/33432482 http://dx.doi.org/10.1007/s11695-020-05219-3 |
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author | Heusschen, Laura Krabbendam, Ineke van der Velde, Jessika M. Deden, Laura N. Aarts, Edo O. Merién, Ashley E. R. Emous, Marloes Bleumink, Gysèle S. Lutgers, Helen L. Hazebroek, Eric J. |
author_facet | Heusschen, Laura Krabbendam, Ineke van der Velde, Jessika M. Deden, Laura N. Aarts, Edo O. Merién, Ashley E. R. Emous, Marloes Bleumink, Gysèle S. Lutgers, Helen L. Hazebroek, Eric J. |
author_sort | Heusschen, Laura |
collection | PubMed |
description | PURPOSE: Current guidelines recommend to avoid pregnancy for 12–24 months after bariatric surgery because of active weight loss and an increased risk of nutritional deficiencies. However, high-quality evidence is lacking, and only a few studies included data on gestational weight gain. We therefore evaluated pregnancy and neonatal outcomes by both surgery-to-conception interval and gestational weight gain. MATERIALS AND METHODS: A multicenter retrospective analysis of 196 singleton pregnancies following Roux-en-Y gastric bypass, sleeve gastrectomy, and one anastomosis gastric bypass was conducted. Pregnancies were divided into the early group (≤ 12 months), the middle group (12–24 months), and the late group (> 24 months) according to the surgery-to-conception interval. Gestational weight gain was classified as inadequate, adequate, or excessive according to the National Academy of Medicine recommendations. RESULTS: Pregnancy in the early group (23.5%) was associated with lower gestational age at delivery (267.1 ± 19.9 days vs 272.7 ± 9.2 and 273.1 ± 13.5 days, P = 0.029), lower gestational weight gain (− 0.9 ± 11.0 kg vs + 10.2 ± 5.6 and + 10.0 ± 6.4 kg, P < 0.001), and lower neonatal birth weight (2979 ± 470 g vs 3161 ± 481 and 3211 ± 465 g, P = 0.008) than pregnancy in the middle and late group. Inadequate gestational weight gain (40.6%) was associated with lower gestational age at delivery (266.5 ± 20.2 days vs 273.8 ± 8.4 days, P = 0.002) and lower neonatal birth weight (3061 ± 511 g vs 3217 ± 479 g, P = 0.053) compared to adequate weight gain. Preterm births were also more frequently observed in this group (15.9% vs 6.0%, P = 0.037). CONCLUSION: Our findings support the recommendation to avoid pregnancy for 12 months after bariatric surgery. Specific attention is needed on achieving adequate gestational weight gain. |
format | Online Article Text |
id | pubmed-8041698 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-80416982021-04-27 A Matter of Timing—Pregnancy After Bariatric Surgery Heusschen, Laura Krabbendam, Ineke van der Velde, Jessika M. Deden, Laura N. Aarts, Edo O. Merién, Ashley E. R. Emous, Marloes Bleumink, Gysèle S. Lutgers, Helen L. Hazebroek, Eric J. Obes Surg Original Contributions PURPOSE: Current guidelines recommend to avoid pregnancy for 12–24 months after bariatric surgery because of active weight loss and an increased risk of nutritional deficiencies. However, high-quality evidence is lacking, and only a few studies included data on gestational weight gain. We therefore evaluated pregnancy and neonatal outcomes by both surgery-to-conception interval and gestational weight gain. MATERIALS AND METHODS: A multicenter retrospective analysis of 196 singleton pregnancies following Roux-en-Y gastric bypass, sleeve gastrectomy, and one anastomosis gastric bypass was conducted. Pregnancies were divided into the early group (≤ 12 months), the middle group (12–24 months), and the late group (> 24 months) according to the surgery-to-conception interval. Gestational weight gain was classified as inadequate, adequate, or excessive according to the National Academy of Medicine recommendations. RESULTS: Pregnancy in the early group (23.5%) was associated with lower gestational age at delivery (267.1 ± 19.9 days vs 272.7 ± 9.2 and 273.1 ± 13.5 days, P = 0.029), lower gestational weight gain (− 0.9 ± 11.0 kg vs + 10.2 ± 5.6 and + 10.0 ± 6.4 kg, P < 0.001), and lower neonatal birth weight (2979 ± 470 g vs 3161 ± 481 and 3211 ± 465 g, P = 0.008) than pregnancy in the middle and late group. Inadequate gestational weight gain (40.6%) was associated with lower gestational age at delivery (266.5 ± 20.2 days vs 273.8 ± 8.4 days, P = 0.002) and lower neonatal birth weight (3061 ± 511 g vs 3217 ± 479 g, P = 0.053) compared to adequate weight gain. Preterm births were also more frequently observed in this group (15.9% vs 6.0%, P = 0.037). CONCLUSION: Our findings support the recommendation to avoid pregnancy for 12 months after bariatric surgery. Specific attention is needed on achieving adequate gestational weight gain. Springer US 2021-01-11 2021 /pmc/articles/PMC8041698/ /pubmed/33432482 http://dx.doi.org/10.1007/s11695-020-05219-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Contributions Heusschen, Laura Krabbendam, Ineke van der Velde, Jessika M. Deden, Laura N. Aarts, Edo O. Merién, Ashley E. R. Emous, Marloes Bleumink, Gysèle S. Lutgers, Helen L. Hazebroek, Eric J. A Matter of Timing—Pregnancy After Bariatric Surgery |
title | A Matter of Timing—Pregnancy After Bariatric Surgery |
title_full | A Matter of Timing—Pregnancy After Bariatric Surgery |
title_fullStr | A Matter of Timing—Pregnancy After Bariatric Surgery |
title_full_unstemmed | A Matter of Timing—Pregnancy After Bariatric Surgery |
title_short | A Matter of Timing—Pregnancy After Bariatric Surgery |
title_sort | matter of timing—pregnancy after bariatric surgery |
topic | Original Contributions |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041698/ https://www.ncbi.nlm.nih.gov/pubmed/33432482 http://dx.doi.org/10.1007/s11695-020-05219-3 |
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