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Upper gastrointestinal tract involvement in Crohn’s disease: A case report
BACKGROUND: Crohn’s disease (CD) is an inflammatory bowel disease that typically affects the distal part of the gastrointestinal tract (GI) such as the terminal ileum and colon. However, it can affect the upper GI tract, potentially resulting in complications such as strictures, but discussion of th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041720/ https://www.ncbi.nlm.nih.gov/pubmed/33887830 http://dx.doi.org/10.1016/j.ijscr.2021.105810 |
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author | Orrell, Michael van 't Hullenaar, Cas Gosling, Jonathan |
author_facet | Orrell, Michael van 't Hullenaar, Cas Gosling, Jonathan |
author_sort | Orrell, Michael |
collection | PubMed |
description | BACKGROUND: Crohn’s disease (CD) is an inflammatory bowel disease that typically affects the distal part of the gastrointestinal tract (GI) such as the terminal ileum and colon. However, it can affect the upper GI tract, potentially resulting in complications such as strictures, but discussion of the management of such effects is limited in the surgical literature. CASE PRESENTATION: A 39 year old male was referred to our department with stricturing upper GI disease 20 years after CD diagnosis. He had a history of intermittent abdominal pain, nausea, frequent vomiting and weight loss. Imaging demonstrated a long stricture in the duodenum with proximal dilatation. There was no evidence of acute inflammatory Crohn’s disease. A Roux-en-Y bypass was performed to successfully relieve the obstructive symptoms. DISCUSSION: Proximal obstructive gastrointestinal manifestations of CD are a rare entity and require a full diagnostic workup and treatment in a specialist centre. A variety of systemic treatments, endoscopic procedures and surgical techniques are addressed in this paper. CONCLUSION: Evidence for the optimal treatment of obstructive upper gastrointestinal CD is limited, but careful consideration of the extent of the disease, thorough preoperative planning and weighing up the benefits and risks can lead to a positive outcome for these patients. |
format | Online Article Text |
id | pubmed-8041720 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-80417202021-04-15 Upper gastrointestinal tract involvement in Crohn’s disease: A case report Orrell, Michael van 't Hullenaar, Cas Gosling, Jonathan Int J Surg Case Rep Case Report BACKGROUND: Crohn’s disease (CD) is an inflammatory bowel disease that typically affects the distal part of the gastrointestinal tract (GI) such as the terminal ileum and colon. However, it can affect the upper GI tract, potentially resulting in complications such as strictures, but discussion of the management of such effects is limited in the surgical literature. CASE PRESENTATION: A 39 year old male was referred to our department with stricturing upper GI disease 20 years after CD diagnosis. He had a history of intermittent abdominal pain, nausea, frequent vomiting and weight loss. Imaging demonstrated a long stricture in the duodenum with proximal dilatation. There was no evidence of acute inflammatory Crohn’s disease. A Roux-en-Y bypass was performed to successfully relieve the obstructive symptoms. DISCUSSION: Proximal obstructive gastrointestinal manifestations of CD are a rare entity and require a full diagnostic workup and treatment in a specialist centre. A variety of systemic treatments, endoscopic procedures and surgical techniques are addressed in this paper. CONCLUSION: Evidence for the optimal treatment of obstructive upper gastrointestinal CD is limited, but careful consideration of the extent of the disease, thorough preoperative planning and weighing up the benefits and risks can lead to a positive outcome for these patients. Elsevier 2021-03-23 /pmc/articles/PMC8041720/ /pubmed/33887830 http://dx.doi.org/10.1016/j.ijscr.2021.105810 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Orrell, Michael van 't Hullenaar, Cas Gosling, Jonathan Upper gastrointestinal tract involvement in Crohn’s disease: A case report |
title | Upper gastrointestinal tract involvement in Crohn’s disease: A case report |
title_full | Upper gastrointestinal tract involvement in Crohn’s disease: A case report |
title_fullStr | Upper gastrointestinal tract involvement in Crohn’s disease: A case report |
title_full_unstemmed | Upper gastrointestinal tract involvement in Crohn’s disease: A case report |
title_short | Upper gastrointestinal tract involvement in Crohn’s disease: A case report |
title_sort | upper gastrointestinal tract involvement in crohn’s disease: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041720/ https://www.ncbi.nlm.nih.gov/pubmed/33887830 http://dx.doi.org/10.1016/j.ijscr.2021.105810 |
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