COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions

Although COVID-19 affects the respiratory system, extrapulmonary manifestations frequently occur, including encephalopathy and liver damage. Here, we want to call attention to a possible connection between liver and brain dysfunctions, in which ammonia can play a role targeting astrocytes. Important...

Descripción completa

Detalles Bibliográficos
Autores principales: Bobermin, Larissa Daniele, Quincozes-Santos, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041743/
https://www.ncbi.nlm.nih.gov/pubmed/33870235
http://dx.doi.org/10.1016/j.bbih.2021.100257
Descripción
Sumario:Although COVID-19 affects the respiratory system, extrapulmonary manifestations frequently occur, including encephalopathy and liver damage. Here, we want to call attention to a possible connection between liver and brain dysfunctions, in which ammonia can play a role targeting astrocytes. Importantly, astrocyte dysfunction can produce future and/or long-term neurological consequences.

Ejemplares similares