COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions

Although COVID-19 affects the respiratory system, extrapulmonary manifestations frequently occur, including encephalopathy and liver damage. Here, we want to call attention to a possible connection between liver and brain dysfunctions, in which ammonia can play a role targeting astrocytes. Important...

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Detalles Bibliográficos
Autores principales: Bobermin, Larissa Daniele, Quincozes-Santos, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041743/
https://www.ncbi.nlm.nih.gov/pubmed/33870235
http://dx.doi.org/10.1016/j.bbih.2021.100257
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author Bobermin, Larissa Daniele
Quincozes-Santos, André
author_facet Bobermin, Larissa Daniele
Quincozes-Santos, André
author_sort Bobermin, Larissa Daniele
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description Although COVID-19 affects the respiratory system, extrapulmonary manifestations frequently occur, including encephalopathy and liver damage. Here, we want to call attention to a possible connection between liver and brain dysfunctions, in which ammonia can play a role targeting astrocytes. Importantly, astrocyte dysfunction can produce future and/or long-term neurological consequences.
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spelling pubmed-80417432021-04-13 COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions Bobermin, Larissa Daniele Quincozes-Santos, André Brain Behav Immun Health Viewpoint Although COVID-19 affects the respiratory system, extrapulmonary manifestations frequently occur, including encephalopathy and liver damage. Here, we want to call attention to a possible connection between liver and brain dysfunctions, in which ammonia can play a role targeting astrocytes. Importantly, astrocyte dysfunction can produce future and/or long-term neurological consequences. Elsevier 2021-04-13 /pmc/articles/PMC8041743/ /pubmed/33870235 http://dx.doi.org/10.1016/j.bbih.2021.100257 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Viewpoint
Bobermin, Larissa Daniele
Quincozes-Santos, André
COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions
title COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions
title_full COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions
title_fullStr COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions
title_full_unstemmed COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions
title_short COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions
title_sort covid-19 and hyperammonemia: potential interplay between liver and brain dysfunctions
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041743/
https://www.ncbi.nlm.nih.gov/pubmed/33870235
http://dx.doi.org/10.1016/j.bbih.2021.100257
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