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Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase

Diguanylate cyclases synthesising the bacterial second messenger c-di-GMP are found to be regulated by a variety of sensory input domains that control the activity of their catalytical GGDEF domain, but how activation proceeds mechanistically is, apart from a few examples, still largely unknown. As...

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Detalles Bibliográficos
Autores principales: Teixeira, Raphael D., Holzschuh, Fabian, Schirmer, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041772/
https://www.ncbi.nlm.nih.gov/pubmed/33846343
http://dx.doi.org/10.1038/s41467-021-22492-7