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Multisubstituted pyrimidines effectively inhibit bacterial growth and biofilm formation of Staphylococcus aureus
Biofilms are multicellular communities of microorganisms that generally attach to surfaces in a self-produced matrix. Unlike planktonic cells, biofilms can withstand conventional antibiotics, causing significant challenges in the healthcare system. Currently, new chemical entities are urgently neede...
Autores principales: | Provenzani, Riccardo, San-Martin-Galindo, Paola, Hassan, Ghada, Legehar, Ashenafi, Kallio, Aleksi, Xhaard, Henri, Fallarero, Adyary, Yli-Kauhaluoma, Jari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041844/ https://www.ncbi.nlm.nih.gov/pubmed/33846401 http://dx.doi.org/10.1038/s41598-021-86852-5 |
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