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Impaired AGO2/miR-185-3p/NRP1 axis promotes colorectal cancer metastasis
Increasing evidence suggests that global downregulation of miRNA expression is a hallmark of human cancer, potentially due to defects in the miRNA processing machinery. In this study, we found that the protein expression of Argonaute 2 (AGO2), a key regulator of miRNA processing, was downregulated i...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042018/ https://www.ncbi.nlm.nih.gov/pubmed/33846300 http://dx.doi.org/10.1038/s41419-021-03672-1 |