mTORC1 mediates fiber type-specific regulation of protein synthesis and muscle size during denervation

Skeletal muscle denervation occurs in diverse conditions and causes severe muscle atrophy. Signaling by mammalian target of rapamycin complex 1 (mTORC1) plays a central role in the maintenance of skeletal muscle mass by regulating net protein balance; yet, its role in denervation-induced atrophy is...

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Detalles Bibliográficos
Autores principales: You, Jae-Sung, Kim, Kookjoo, Steinert, Nathaniel D., Chen, Jie, Hornberger, Troy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042034/
https://www.ncbi.nlm.nih.gov/pubmed/33846288
http://dx.doi.org/10.1038/s41420-021-00460-w

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