Human anogenital monocyte-derived dendritic cells and langerin+cDC2 are major HIV target cells

Tissue mononuclear phagocytes (MNP) are specialised in pathogen detection and antigen presentation. As such they deliver HIV to its primary target cells; CD4 T cells. Most MNP HIV transmission studies have focused on epithelial MNPs. However, as mucosal trauma and inflammation are now known to be st...

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Detalles Bibliográficos
Autores principales: Rhodes, Jake W., Botting, Rachel A., Bertram, Kirstie M., Vine, Erica E., Rana, Hafsa, Baharlou, Heeva, Vegh, Peter, O’Neil, Thomas R., Ashhurst, Anneliese S., Fletcher, James, Parnell, Grant P., Graham, J. Dinny, Nasr, Najla, Lim, Jake J. K., Barnouti, Laith, Haertsch, Peter, Gosselink, Martijn P., Di Re, Angelina, Reza, Faizur, Ctercteko, Grahame, Jenkins, Gregory J., Brooks, Andrew J., Patrick, Ellis, Byrne, Scott N., Hunter, Eric, Haniffa, Muzlifah A., Cunningham, Anthony L., Harman, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042121/
https://www.ncbi.nlm.nih.gov/pubmed/33846309
http://dx.doi.org/10.1038/s41467-021-22375-x

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