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Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity

Alterations in mitochondrial fission may contribute to the pathophysiology of several neurodegenerative diseases, including Alzheimer’s disease (AD). However, we understand very little about the normal functions of fission or how fission disruption may interact with AD-associated proteins to modulat...

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Detalles Bibliográficos
Autores principales: Shields, Lauren Y., Li, Huihui, Nguyen, Kevin, Kim, Hwajin, Doric, Zak, Garcia, Joseph H., Gill, T. Michael, Haddad, Dominik, Vossel, Keith, Calvert, Meredith, Nakamura, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042169/
https://www.ncbi.nlm.nih.gov/pubmed/33639169
http://dx.doi.org/10.1016/j.jbc.2021.100469

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