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Expression of Novel L-Leucine Dehydrogenase and High-Level Production of L-Tert-Leucine Catalyzed by Engineered Escherichia coli

Leucine dehydrogenase (LDH) is a NAD(+)-dependent oxidoreductase, which can selectively catalyze α-keto acids to obtain α-amino acids and their derivatives. It plays a key role in the biosynthesis of L-tert-leucine (L-Tle). As a non-naturally chiral amino acid, L-Tle can be used as an animal feed ad...

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Detalles Bibliográficos
Autores principales:	Jia, Yuan-Yuan, Xie, Yu-Li, Yang, Lu-Lu, Shi, Hong-Ling, Lu, Yun-Feng, Zhang, Si-Pu, Tang, Cun-Duo, Yao, Lun-Guang, Kan, Yun-Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042219/ https://www.ncbi.nlm.nih.gov/pubmed/33859982 http://dx.doi.org/10.3389/fbioe.2021.655522

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