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Replication-stress-associated DSBs induced by ionizing radiation risk genomic destabilization and associated clonal evolution
Exposure to ionizing radiation is associated with cancer risk. Although multiple types of DNA damage are caused by radiation, it remains unknown how this damage is associated with cancer risk. Here, we show that after repair of double-strand breaks (DSBs) directly caused by radiation (dir-DSBs), irr...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042347/ https://www.ncbi.nlm.nih.gov/pubmed/33870130 http://dx.doi.org/10.1016/j.isci.2021.102313 |