Cargando…
Very long chain fatty acid-containing lipids: a decade of novel insights from the study of ELOVL4
Lipids play essential roles in maintaining cell structure and function by modulating membrane fluidity and cell signaling. The fatty acid elongase-4 (ELOVL4) protein, expressed in retina, brain, Meibomian glands, skin, testes and sperm, is an essential enzyme that mediates tissue-specific biosynthes...
Autores principales: | Yeboah, Gyening Kofi, Lobanova, Ekaterina S., Brush, Richard S., Agbaga, Martin-Paul |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042400/ https://www.ncbi.nlm.nih.gov/pubmed/33556440 http://dx.doi.org/10.1016/j.jlr.2021.100030 |
Ejemplares similares
-
ELOVL4 Mutations That Cause Spinocerebellar Ataxia-34 Differentially Alter Very Long Chain Fatty Acid Biosynthesis
por: Gyening, Yeboah Kofi, et al.
Publicado: (2022) -
A novel ELOVL4 variant, L168S, causes early childhood-onset Spinocerebellar ataxia-34 and retinal dysfunction: a case report
por: Gyening, Yeboah Kofi, et al.
Publicado: (2023) -
ELOVL4: Very long-chain fatty acids serve an eclectic role in mammalian health and function
por: Hopiavuori, Blake R., et al.
Publicado: (2018) -
Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity
por: Logan, Sreemathi, et al.
Publicado: (2014) -
Homozygous Expression of Mutant ELOVL4 Leads to Seizures and Death in a Novel Animal Model of Very Long-Chain Fatty Acid Deficiency
por: Hopiavuori, Blake R., et al.
Publicado: (2017)