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Lipid remodeling in response to methionine stress in MDA-MBA-468 triple-negative breast cancer cells
Methionine (Met) is an essential amino acid and critical precursor to the cellular methyl donor S-adenosylmethionine. Unlike nontransformed cells, cancer cells have a unique metabolic requirement for Met and are unable to proliferate in growth media where Met is replaced with its metabolic precursor...
Autores principales: | Borrego, Stacey L., Fahrmann, Johannes, Hou, Jue, Lin, Da-Wei, Tromberg, Bruce J., Fiehn, Oliver, Kaiser, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042402/ https://www.ncbi.nlm.nih.gov/pubmed/33647277 http://dx.doi.org/10.1016/j.jlr.2021.100056 |
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