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A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding
PDZ domains are one of the most abundant protein domains in eukaryotes and are frequently found on junction-localized scaffold proteins. Various signaling molecules bind to PDZ proteins via PDZ-binding motifs (PBM) and fine-tune cellular signaling. However, how such interaction affects protein funct...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042451/ https://www.ncbi.nlm.nih.gov/pubmed/33675748 http://dx.doi.org/10.1016/j.jbc.2021.100493 |