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A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding

PDZ domains are one of the most abundant protein domains in eukaryotes and are frequently found on junction-localized scaffold proteins. Various signaling molecules bind to PDZ proteins via PDZ-binding motifs (PBM) and fine-tune cellular signaling. However, how such interaction affects protein funct...

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Detalles Bibliográficos
Autores principales:	Ear, Jason, Abd El-Hafeez, Amer Ali, Roy, Suchismita, Ngo, Tony, Rajapakse, Navin, Choi, Julie, Khandelwal, Soni, Ghassemian, Majid, McCaffrey, Luke, Kufareva, Irina, Sahoo, Debashis, Ghosh, Pradipta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042451/ https://www.ncbi.nlm.nih.gov/pubmed/33675748 http://dx.doi.org/10.1016/j.jbc.2021.100493

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