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IFN-λ4 is associated with increased risk and earlier occurrence of several common infections in African children
Genetic polymorphisms within the IFNL3/IFNL4 genomic region, which encodes type III interferons, have been strongly associated with clearance of hepatitis C virus. We hypothesized that type III interferons might be important for the immune response to other pathogens as well. In a cohort of 914 Mali...
Autores principales: | Prokunina-Olsson, Ludmila, Morrison, Robert D., Obajemu, Adeola, Mahamar, Almahamoudou, Kim, Sungduk, Attaher, Oumar, Florez-Vargas, Oscar, Sidibe, Youssoufa, Onabajo, Olusegun O., Hutchinson, Amy A., Manning, Michelle, Kwan, Jennifer, Brand, Nathan, Dicko, Alassane, Fried, Michal, Albert, Paul S., Mbulaiteye, Sam M., Duffy, Patrick E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042471/ https://www.ncbi.nlm.nih.gov/pubmed/33850301 http://dx.doi.org/10.1038/s41435-021-00127-7 |
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