Cargando…
Transcriptional signatures underlying dynamic phenotypic switching and novel disease biomarkers in a linear cellular model of melanoma progression
Despite advances in therapeutics, the progression of melanoma to metastasis still confers a poor outcome to patients. Nevertheless, there is a scarcity of biological models to understand cellular and molecular changes taking place along disease progression. Here, we characterized the transcriptome p...
Autores principales: | Pessoa, Diogo de Oliveira, Rius, Flávia Eichemberger, Papaiz, Debora D'Angelo, Ayub, Ana Luísa Pedroso, Morais, Alice Santana, de Souza, Camila Ferreira, da Paixão, Vinicius Ferreira, Setubal, João Carlos, Newton-Bishop, Julia, Nsengimana, Jérémie, Azevedo, Hatylas, Reis, Eduardo Moraes, Jasiulionis, Miriam Galvonas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042650/ https://www.ncbi.nlm.nih.gov/pubmed/33845354 http://dx.doi.org/10.1016/j.neo.2021.03.007 |
Ejemplares similares
-
Genes regulated by DNA methylation are involved in distinct phenotypes during melanoma progression and are prognostic factors for patients
por: Papaiz, Debora D’Angelo, et al.
Publicado: (2022) -
Gene co-expression and histone modification signatures are associated with melanoma progression, epithelial-to-mesenchymal transition, and metastasis
por: Azevedo, Hátylas, et al.
Publicado: (2020) -
Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival
por: Rius, Flávia E., et al.
Publicado: (2022) -
Biomarkers as Key Contributors in Treating Malignant Melanoma Metastases
por: de Souza, Camila Ferreira, et al.
Publicado: (2012) -
Gene expression and promoter methylation of angiogenic and lymphangiogenic factors as prognostic markers in melanoma
por: Monteiro, Ana Carolina, et al.
Publicado: (2019)