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Ros3 (Lem3p/CDC50) Gene Dosage Is Implicated in Miltefosine Susceptibility in Leishmania (Viannia) braziliensis Clinical Isolates and in Leishmania (Leishmania) major

[Image: see text] The Ros3 protein is a component of the MT-Ros3 transporter complex, considered as the main route of miltefosine entry in Leishmania. L. braziliensis clinical isolates presenting differences in miltefosine susceptibility and uptake were previously shown to differentially express ros...

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Detalles Bibliográficos
Autores principales:	Espada, Caroline R., Albuquerque-Wendt, Andreia, Hornillos, Valentín, Gluenz, Eva, Coelho, Adriano C., Uliana, Silvia R. B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042657/ https://www.ncbi.nlm.nih.gov/pubmed/33724800 http://dx.doi.org/10.1021/acsinfecdis.0c00857

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