Violacein-Induced Chaperone System Collapse Underlies Multistage Antiplasmodial Activity

[Image: see text] Antimalarial drugs with novel modes of action and wide therapeutic potential are needed to pave the way for malaria eradication. Violacein is a natural compound known for its biological activity against cancer cells and several pathogens, including the malaria parasite, Plasmodium...

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Autores principales: Tavella, Tatyana Almeida, da Silva, Noeli Soares Melo, Spillman, Natalie, Kayano, Ana Carolina Andrade Vitor, Cassiano, Gustavo Capatti, Vasconcelos, Adrielle Ayumi, Camargo, Antônio Pedro, da Silva, Djane Clarys Baia, Fontinha, Diana, Salazar Alvarez, Luis Carlos, Ferreira, Letícia Tiburcio, Peralis Tomaz, Kaira Cristina, Neves, Bruno Junior, Almeida, Ludimila Dias, Bargieri, Daniel Youssef, Lacerda, Marcus Vinicius Guimarães de, Lemos Cravo, Pedro Vitor, Sunnerhagen, Per, Prudêncio, Miguel, Andrade, Carolina Horta, Pinto Lopes, Stefanie Costa, Carazzolle, Marcelo Falsarella, Tilley, Leann, Bilsland, Elizabeth, Borges, Júlio César, Maranhão Costa, Fabio Trindade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042658/
https://www.ncbi.nlm.nih.gov/pubmed/33689276
http://dx.doi.org/10.1021/acsinfecdis.0c00454

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