Cargando…

Stomatin-like protein 2 induces metastasis by regulating the expression of a rate-limiting enzyme of the hexosamine biosynthetic pathway in pancreatic cancer

Stomatin-like protein 2 (SLP-2) is associated with poor prognosis in several types of cancer, including pancreatic cancer (PC); however, the molecular mechanism of its involvement remains elusive. The present study aimed to elucidate the role of this protein in the development of PC. Human PC cell l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chao, Dang, Ariake, Kyohei, Sato, Satoko, Ohtsuka, Hideo, Takadate, Tatsuyuki, Ishida, Masaharu, Masuda, Kunihiro, Maeda, Shimpei, Miura, Takayuki, Mitachi, Katsutaka, Yu, Xun Jing, Fujishima, Fumiyoshi, Mizuma, Masamichi, Nakagawa, Kei, Morikawa, Takanori, Kamei, Takashi, Unno, Michiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042670/ https://www.ncbi.nlm.nih.gov/pubmed/33846782 http://dx.doi.org/10.3892/or.2021.8041

Ejemplares similares

Novel candidate factors predicting the effect of S-1 adjuvant chemotherapy of pancreatic cancer
por: Mitachi, Katsutaka, et al.
Publicado: (2021)

Increased neutrophil–lymphocyte ratio predicts recurrence in patients with well-differentiated pancreatic neuroendocrine neoplasm based on the 2017 World Health Organization classification
por: Miura, Takayuki, et al.
Publicado: (2021)

Probiotic-related bacteremia after major hepatectomy for biliary cancer: a report of two cases
por: Shimura, Mitsuhiro, et al.
Publicado: (2021)

Locally advanced pancreatic cancer successfully treated by distal pancreatectomy with celiac axis resection (DP-CAR) after S-1 with radiation therapy followed by gemcitabine/nab-paclitaxel therapy: a case report
por: Ariake, Kyohei, et al.
Publicado: (2017)

A long-term survival case treated with conversion surgery following chemotherapy after diagnostic metastasectomy for pancreatic cancer with synchronous liver metastasis
por: Shimura, Mitsuhiro, et al.
Publicado: (2017)

FBXW7 modulates malignant potential and cisplatin‐induced apoptosis in cholangiocarcinoma through NOTCH1 and MCL1
por: Mori, Akiko, et al.
Publicado: (2018)

Pancreatic neuroendocrine tumor with complete replacement of the pancreas by serous cystic neoplasms in a patient with von Hippel-Lindau disease: a case report
por: Maeda, Shimpei, et al.
Publicado: (2017)

Metastasis of ovarian cancer to the bile duct: a case report
por: Shijo, Masahiro, et al.
Publicado: (2019)

Reduced expression of phosphorylated ataxia-telangiectasia mutated gene is related to poor prognosis and gemcitabine chemoresistance in pancreatic cancer
por: Xun, Jingyu, et al.
Publicado: (2023)

Protein‐arginine deiminase 2 suppresses proliferation of colon cancer cells through protein citrullination
por: Funayama, Ryo, et al.
Publicado: (2017)

Germline DNA damage repair gene mutations in pancreatic cancer patients with personal/family histories of pancreas/breast/ovarian/prostate cancer in a Japanese population
por: Hata, Tatsuo, et al.
Publicado: (2021)

A long-term survivor of metachronous liver metastases of pancreatic serous cystic neoplasm associated with von Hippel–Lindau disease
por: Kokumai, Takashi, et al.
Publicado: (2021)

Levels of tumor markers CEA/CA 19–9 in serum and peritoneal lavage predict postoperative recurrence in patients with pancreatic cancer
por: Hata, Tatsuo, et al.
Publicado: (2022)

Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer
por: Akella, Neha M., et al.
Publicado: (2019)

The dual role of the hexosamine biosynthetic pathway in cardiac physiology and pathophysiology
por: Cairns, Megan, et al.
Publicado: (2022)

Defining the Optimal Method for Measuring Metabolic Tumor Volume on Preoperative (18)F-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography as a Prognostic Predictor in Patients With Pancreatic Ductal Adenocarcinoma
por: Tatewaki, Yasuko, et al.
Publicado: (2021)

A novel liver metastasis-correlated protein of pancreatic neuroendocrine neoplasm (PanNEN) discovered by proteomic analysis
por: Shimura, Mitsuhiro, et al.
Publicado: (2018)

Pancreaticoduodenectomy for pancreatic head cancer with cavernous transformation of the portal vein: a case report
por: Hirano, Naohiro, et al.
Publicado: (2022)

GNAS mutation detection in circulating cell-free DNA is a specific predictor for intraductal papillary mucinous neoplasms of the pancreas, especially for intestinal subtype
por: Hata, Tatsuo, et al.
Publicado: (2020)

Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer
por: Kaushik, Akash K., et al.
Publicado: (2016)

Hijacking the Hexosamine Biosynthetic Pathway to Promote EMT-Mediated Neoplastic Phenotypes
por: Taparra, Kekoa, et al.
Publicado: (2016)

Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways
por: Ryczko, Michael C., et al.
Publicado: (2016)

Differential hexosamine biosynthetic pathway gene expression with type 2 diabetes
por: Coomer, Megan, et al.
Publicado: (2014)

The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring
por: Chiaradonna, Ferdinando, et al.
Publicado: (2018)

Hexosamine Biosynthetic Pathway and Glycosylation Regulate Cell Migration in Melanoma Cells
por: de Queiroz, Rafaela Muniz, et al.
Publicado: (2019)

Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway
por: Vasconcelos-dos-Santos, A, et al.
Publicado: (2017)

Ral GTPase–activating protein regulates the malignancy of pancreatic ductal adenocarcinoma
por: Yoshimachi, Shingo, et al.
Publicado: (2021)

Disease-related protein co-expression networks are associated with the prognosis of resectable node-positive pancreatic ductal adenocarcinoma
por: Nishimura, Toshihide, et al.
Publicado: (2022)

Salvage esophagectomy for local recurrent esophageal cancer after definitive chemoradiotherapy followed by photodynamic therapy: A case report
por: Hirose, Wataru, et al.
Publicado: (2021)

Rapidly growing carcinosarcoma of the esophagus following definitive chemoradiotherapy: A case report and the literature review
por: Yamauchi, Takuro, et al.
Publicado: (2022)

Glycolysis and the Hexosamine Biosynthetic Pathway as Novel Targets for Upper and Lower Airway Inflammation
por: Kim, Young Hyo, et al.
Publicado: (2018)

A case of adult undifferentiated embryonal sarcoma of the liver successfully treated with right trisectionectomy: a case report
por: Mori, Akiko, et al.
Publicado: (2017)

Novel biomarkers distinguishing pancreatic head Cancer from distal cholangiocarcinoma based on proteomic analysis
por: Takenami, Tsutomu, et al.
Publicado: (2019)

Stromal expression of hemopexin is associated with lymph-node metastasis in pancreatic ductal adenocarcinoma
por: Suzuki, Yukie, et al.
Publicado: (2020)

The Hexosamine Biosynthetic Pathway Links Innate Inflammation With Epithelial-Mesenchymal Plasticity in Airway Remodeling
por: Brasier, Allan R., et al.
Publicado: (2021)

Contribution of the hexosamine biosynthetic pathway in the hyperglycemia-dependent and -independent breakdown of the retinal neurovascular unit
por: Wang, Yixin, et al.
Publicado: (2023)

Targeting the Hexosamine Biosynthetic Pathway Prevents Plasmodium Developmental Cycle and Disease Pathology in Vertebrate Host
por: Gomes, Pollyanna Stephanie, et al.
Publicado: (2019)

Roles of the hexosamine biosynthetic pathway and pentose phosphate pathway in bile acid‐induced cancer development
por: Munemoto, Masayoshi, et al.
Publicado: (2019)

Hexosamine Biosynthetic Pathway-Derived O-GlcNAcylation Is Critical for RANKL-Mediated Osteoclast Differentiation
por: Kim, Myoung Jun, et al.
Publicado: (2021)

Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway
por: Chaveroux, Cédric, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_kdbgum61uatbkvl10311jq1dls