PD-L1 lncRNA splice isoform promotes lung adenocarcinoma progression via enhancing c-Myc activity

BACKGROUND: Although using a blockade of programmed death-ligand 1 (PD-L1) to enhance T cell immune responses shows great promise in tumor immunotherapy, the immune-checkpoint inhibition strategy is limited for patients with solid tumors. The mechanism and efficacy of such immune-checkpoint inhibiti...

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Detalles Bibliográficos
Autores principales: Qu, Shuang, Jiao, Zichen, Lu, Geng, Yao, Bing, Wang, Ting, Rong, Weiwei, Xu, Jiahan, Fan, Ting, Sun, Xinlei, Yang, Rong, Wang, Jun, Yao, Yongzhong, Xu, Guifang, Yan, Xin, Wang, Tao, Liang, Hongwei, Zen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042710/
https://www.ncbi.nlm.nih.gov/pubmed/33849634
http://dx.doi.org/10.1186/s13059-021-02331-0

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