Cargando…

Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs

Neuromodulation of the immune system has been proposed as a novel therapeutic strategy for the treatment of inflammatory conditions. We recently demonstrated that stimulation of near-organ autonomic nerves to the spleen can be harnessed to modulate the inflammatory response in an anesthetized pig mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sokal, David M., McSloy, Alex, Donegà, Matteo, Kirk, Joseph, Colas, Romain A., Dolezalova, Nikola, Gomez, Esteban A., Gupta, Isha, Fjordbakk, Cathrine T., Ouchouche, Sebastien, Matteucci, Paul B., Schlegel, Kristina, Bashirullah, Rizwan, Werling, Dirk, Harman, Kim, Rowles, Alison, Yazicioglu, Refet Firat, Dalli, Jesmond, Chew, Daniel J., Perkins, Justin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043071/ https://www.ncbi.nlm.nih.gov/pubmed/33859641 http://dx.doi.org/10.3389/fimmu.2021.649786

Ejemplares similares

Human-relevant near-organ neuromodulation of the immune system via the splenic nerve
por: Donegà, Matteo, et al.
Publicado: (2021)

Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves
por: Gupta, Isha, et al.
Publicado: (2020)

Feasibility of kilohertz frequency alternating current neuromodulation of carotid sinus nerve activity in the pig
por: Fjordbakk, Cathrine T., et al.
Publicado: (2019)

Ultrasound-guided psoas compartment and sciatic nerve blocks for pain management of hind limb procedures in the alpaca (Vicugna pacos)
por: Foster, Andrew, et al.
Publicado: (2020)

Splenic arterial neurovascular bundle stimulation in esophagectomy: A feasibility and safety prospective cohort study
por: Brinkman, David J., et al.
Publicado: (2022)

CORRIGENDUM: Novel n-3 Immunoresolvents: Structures and Actions
por: Dalli, Jesmond, et al.
Publicado: (2014)

Novel n-3 Immunoresolvents: Structures and Actions
por: Dalli, Jesmond, et al.
Publicado: (2013)

Identification of resolvin D2 receptor mediating resolution of infections and organ protection
por: Chiang, Nan, et al.
Publicado: (2015)

Protective activities of distinct omega-3 enriched oils are linked to their ability to upregulate specialized pro-resolving mediators
por: Sobrino, Agua, et al.
Publicado: (2020)

13-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis
por: Walker, Mary E., et al.
Publicado: (2017)

The equine patellar ligaments and the infrapatellar fat pad – a microanatomical study
por: Fjordbakk, Cathrine Taule, et al.
Publicado: (2023)

Immunoresolvents signaling molecules at intersection between the brain and immune system
por: Dalli, Jesmond, et al.
Publicado: (2018)

Pro-Resolving Mediators in Regulating and Conferring Macrophage Function
por: Dalli, Jesmond, et al.
Publicado: (2017)

Identification and structure elucidation of the pro‐resolving mediators provides novel leads for resolution pharmacology
por: Dalli, Jesmond, et al.
Publicado: (2018)

Reply to: Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples
por: Dalli, Jesmond, et al.
Publicado: (2023)

Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis
por: Flak, Magdalena B., et al.
Publicado: (2019)

Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis
por: Flak, Magdalena B., et al.
Publicado: (2022)

Prolonged immune alteration following resolution of acute inflammation in humans
por: Motwani, Madhur P., et al.
Publicado: (2017)

Distinct immune profiles of HIV‐infected subjects are linked to specific lipid mediator signature
por: Sips, Magdalena, et al.
Publicado: (2022)

Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections
por: Dalli, Jesmond, et al.
Publicado: (2015)

Dysregulated Maresin Concentrations in Plasma and Nasal Secretions From Patients With Chronic Rhinosinusitis
por: Beegun, Issa, et al.
Publicado: (2021)

Utility of the Specialized Pro-Resolving Mediators as Diagnostic and Prognostic Biomarkers in Disease
por: Dalli, Jesmond, et al.
Publicado: (2022)

Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy
por: Dakin, Stephanie G., et al.
Publicado: (2017)

Treatment With a Marine Oil Supplement Alters Lipid Mediators and Leukocyte Phenotype in Healthy Patients and Those With Peripheral Artery Disease
por: Schaller, Melinda S., et al.
Publicado: (2020)

Aspirin activates resolution pathways to reprogram T cell and macrophage responses in colitis-associated colorectal cancer
por: De Matteis, Roberta, et al.
Publicado: (2022)

Synthesis and Anti-inflammatory and Pro-resolving Activities of 22-OH-PD1, a Monohydroxylated Metabolite of Protectin D1
por: Tungen, Jørn E., et al.
Publicado: (2014)

Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis
por: Gomez, Esteban A., et al.
Publicado: (2020)

Annexin A1 N-Terminal Derived Peptide Ac2-26 Exerts Chemokinetic Effects on Human Neutrophils
por: Dalli, Jesmond, et al.
Publicado: (2012)

Human Milk Proresolving Mediators Stimulate Resolution of Acute Inflammation
por: Arnardottir, Hildur, et al.
Publicado: (2015)

Characterizing the anti-inflammatory and tissue protective actions of a novel Annexin A1 peptide
por: Perretti, Mauro, et al.
Publicado: (2017)

Total Synthesis of the Lipid Mediator PD1(n-3 DPA): Configurational Assignments and Anti-inflammatory and Pro-resolving Actions
por: Aursnes, Marius, et al.
Publicado: (2014)

Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins
por: Primdahl, Karoline G., et al.
Publicado: (2016)

HIF1α activation in dendritic cells under sterile conditions promotes an anti-inflammatory phenotype through accumulation of intracellular lipids
por: Wood, Elizabeth G., et al.
Publicado: (2020)

Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins
por: Cianci, Eleonora, et al.
Publicado: (2016)

Loss of 15-lipoxygenase disrupts T(reg) differentiation altering their pro-resolving functions
por: Marques, Raquel M., et al.
Publicado: (2021)

Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA
por: Fredman, Gabrielle, et al.
Publicado: (2012)

Vagus nerve controls resolution and pro-resolving mediators of inflammation
por: Mirakaj, Valbona, et al.
Publicado: (2014)

Arachidonate 15-lipoxygenase-mediated production of Resolvin D5(n-3 DPA) abrogates pancreatic stellate cell-induced cancer cell invasion
por: Aguirre, Gabriel A., et al.
Publicado: (2023)

Neuromodulation for cephalgias
por: Rasskazoff, Serge Y., et al.
Publicado: (2013)

Neuromodulation of Attention
por: Thiele, Alexander, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_01lrnuhec0jh7u1ofoeob3i0cc