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Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 alveolar macrophages

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades the alveoli, where abundant alveolar macrophages (AMs) reside. How AMs respond to SARS-CoV-2 invasion remains elusive. Here, we show that classically activated M1 AMs facilitate viral spread; however, alternatively activated M2 AMs...

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Detalles Bibliográficos
Autores principales: Lv, Jiadi, Wang, Zhenfeng, Qu, Yajin, Zhu, Hua, Zhu, Qiangqiang, Tong, Wei, Bao, Linlin, Lv, Qi, Cong, Ji, Li, Dan, Deng, Wei, Yu, Pin, Song, Jiangping, Tong, Wei-Min, Liu, Jiangning, Liu, Yuying, Qin, Chuan, Huang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043100/
https://www.ncbi.nlm.nih.gov/pubmed/33850112
http://dx.doi.org/10.1038/s41421-021-00258-1

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