Cargando…

Sex Disparities in Cardiovascular Risk Factor Assessment and Screening for Diabetes-Related Complications in Individuals With Diabetes: A Systematic Review

BACKGROUND: Insight in sex disparities in the detection of cardiovascular risk factors and diabetes-related complications may improve diabetes care. The aim of this systematic review is to study whether sex disparities exist in the assessment of cardiovascular risk factors and screening for diabetes...

Descripción completa

Detalles Bibliográficos
Autores principales: de Jong, Marit, Peters, Sanne A. E., de Ritter, Rianneke, van der Kallen, Carla J. H., Sep, Simone J. S., Woodward, Mark, Stehouwer, Coen D. A., Bots, Michiel L., Vos, Rimke C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043152/
https://www.ncbi.nlm.nih.gov/pubmed/33859615
http://dx.doi.org/10.3389/fendo.2021.617902
_version_ 1783678259360169984
author de Jong, Marit
Peters, Sanne A. E.
de Ritter, Rianneke
van der Kallen, Carla J. H.
Sep, Simone J. S.
Woodward, Mark
Stehouwer, Coen D. A.
Bots, Michiel L.
Vos, Rimke C.
author_facet de Jong, Marit
Peters, Sanne A. E.
de Ritter, Rianneke
van der Kallen, Carla J. H.
Sep, Simone J. S.
Woodward, Mark
Stehouwer, Coen D. A.
Bots, Michiel L.
Vos, Rimke C.
author_sort de Jong, Marit
collection PubMed
description BACKGROUND: Insight in sex disparities in the detection of cardiovascular risk factors and diabetes-related complications may improve diabetes care. The aim of this systematic review is to study whether sex disparities exist in the assessment of cardiovascular risk factors and screening for diabetes-related complications. METHODS: PubMed was systematically searched up to April 2020, followed by manual reference screening and citations checks (snowballing) using Google Scholar. Observational studies were included if they reported on the assessment of cardiovascular risk factors (HbA1c, lipids, blood pressure, smoking status, or BMI) and/or screening for nephropathy, retinopathy, or performance of feet examinations, in men and women with diabetes separately. Studies adjusting their analyses for at least age, or when age was considered as a covariable but left out from the final analyses for various reasons (i.e. backward selection), were included for qualitative analyses. No meta-analyses were planned because substantial heterogeneity between studies was expected. A modified Newcastle-Ottawa Quality Assessment Scale for cohort studies was used to assess risk of bias. RESULTS: Overall, 81 studies were included. The majority of the included studies were from Europe or North America (84%).The number of individuals per study ranged from 200 to 3,135,019 and data were extracted from various data sources in a variety of settings. Screening rates varied considerably across studies. For example, screening rates for retinopathy ranged from 13% to 90%, with half the studies reporting screening rates less than 50%. Mixed findings were found regarding the presence, magnitude, and direction of sex disparities with regard to the assessment of cardiovascular risk factors and screening for diabetes-related complications, with some evidence suggesting that women, compared with men, may be more likely to receive retinopathy screening and less likely to receive foot exams. CONCLUSION: Overall, no consistent pattern favoring men or women was found with regard to the assessment of cardiovascular risk factors and screening for diabetes-related complications, and screening rates can be improved for both sexes.
format Online
Article
Text
id pubmed-8043152
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-80431522021-04-14 Sex Disparities in Cardiovascular Risk Factor Assessment and Screening for Diabetes-Related Complications in Individuals With Diabetes: A Systematic Review de Jong, Marit Peters, Sanne A. E. de Ritter, Rianneke van der Kallen, Carla J. H. Sep, Simone J. S. Woodward, Mark Stehouwer, Coen D. A. Bots, Michiel L. Vos, Rimke C. Front Endocrinol (Lausanne) Endocrinology BACKGROUND: Insight in sex disparities in the detection of cardiovascular risk factors and diabetes-related complications may improve diabetes care. The aim of this systematic review is to study whether sex disparities exist in the assessment of cardiovascular risk factors and screening for diabetes-related complications. METHODS: PubMed was systematically searched up to April 2020, followed by manual reference screening and citations checks (snowballing) using Google Scholar. Observational studies were included if they reported on the assessment of cardiovascular risk factors (HbA1c, lipids, blood pressure, smoking status, or BMI) and/or screening for nephropathy, retinopathy, or performance of feet examinations, in men and women with diabetes separately. Studies adjusting their analyses for at least age, or when age was considered as a covariable but left out from the final analyses for various reasons (i.e. backward selection), were included for qualitative analyses. No meta-analyses were planned because substantial heterogeneity between studies was expected. A modified Newcastle-Ottawa Quality Assessment Scale for cohort studies was used to assess risk of bias. RESULTS: Overall, 81 studies were included. The majority of the included studies were from Europe or North America (84%).The number of individuals per study ranged from 200 to 3,135,019 and data were extracted from various data sources in a variety of settings. Screening rates varied considerably across studies. For example, screening rates for retinopathy ranged from 13% to 90%, with half the studies reporting screening rates less than 50%. Mixed findings were found regarding the presence, magnitude, and direction of sex disparities with regard to the assessment of cardiovascular risk factors and screening for diabetes-related complications, with some evidence suggesting that women, compared with men, may be more likely to receive retinopathy screening and less likely to receive foot exams. CONCLUSION: Overall, no consistent pattern favoring men or women was found with regard to the assessment of cardiovascular risk factors and screening for diabetes-related complications, and screening rates can be improved for both sexes. Frontiers Media S.A. 2021-03-30 /pmc/articles/PMC8043152/ /pubmed/33859615 http://dx.doi.org/10.3389/fendo.2021.617902 Text en Copyright © 2021 de Jong, Peters, de Ritter, van der Kallen, Sep, Woodward, Stehouwer, Bots and Vos https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
de Jong, Marit
Peters, Sanne A. E.
de Ritter, Rianneke
van der Kallen, Carla J. H.
Sep, Simone J. S.
Woodward, Mark
Stehouwer, Coen D. A.
Bots, Michiel L.
Vos, Rimke C.
Sex Disparities in Cardiovascular Risk Factor Assessment and Screening for Diabetes-Related Complications in Individuals With Diabetes: A Systematic Review
title Sex Disparities in Cardiovascular Risk Factor Assessment and Screening for Diabetes-Related Complications in Individuals With Diabetes: A Systematic Review
title_full Sex Disparities in Cardiovascular Risk Factor Assessment and Screening for Diabetes-Related Complications in Individuals With Diabetes: A Systematic Review
title_fullStr Sex Disparities in Cardiovascular Risk Factor Assessment and Screening for Diabetes-Related Complications in Individuals With Diabetes: A Systematic Review
title_full_unstemmed Sex Disparities in Cardiovascular Risk Factor Assessment and Screening for Diabetes-Related Complications in Individuals With Diabetes: A Systematic Review
title_short Sex Disparities in Cardiovascular Risk Factor Assessment and Screening for Diabetes-Related Complications in Individuals With Diabetes: A Systematic Review
title_sort sex disparities in cardiovascular risk factor assessment and screening for diabetes-related complications in individuals with diabetes: a systematic review
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043152/
https://www.ncbi.nlm.nih.gov/pubmed/33859615
http://dx.doi.org/10.3389/fendo.2021.617902
work_keys_str_mv AT dejongmarit sexdisparitiesincardiovascularriskfactorassessmentandscreeningfordiabetesrelatedcomplicationsinindividualswithdiabetesasystematicreview
AT peterssanneae sexdisparitiesincardiovascularriskfactorassessmentandscreeningfordiabetesrelatedcomplicationsinindividualswithdiabetesasystematicreview
AT deritterrianneke sexdisparitiesincardiovascularriskfactorassessmentandscreeningfordiabetesrelatedcomplicationsinindividualswithdiabetesasystematicreview
AT vanderkallencarlajh sexdisparitiesincardiovascularriskfactorassessmentandscreeningfordiabetesrelatedcomplicationsinindividualswithdiabetesasystematicreview
AT sepsimonejs sexdisparitiesincardiovascularriskfactorassessmentandscreeningfordiabetesrelatedcomplicationsinindividualswithdiabetesasystematicreview
AT woodwardmark sexdisparitiesincardiovascularriskfactorassessmentandscreeningfordiabetesrelatedcomplicationsinindividualswithdiabetesasystematicreview
AT stehouwercoenda sexdisparitiesincardiovascularriskfactorassessmentandscreeningfordiabetesrelatedcomplicationsinindividualswithdiabetesasystematicreview
AT botsmichiell sexdisparitiesincardiovascularriskfactorassessmentandscreeningfordiabetesrelatedcomplicationsinindividualswithdiabetesasystematicreview
AT vosrimkec sexdisparitiesincardiovascularriskfactorassessmentandscreeningfordiabetesrelatedcomplicationsinindividualswithdiabetesasystematicreview