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Caffeine-clozapine interaction associated with severe toxicity and multiorgan system failure: a case report
BACKGROUND: Caffeine is a known inhibitor of Clozapine metabolism mediated by inhibition of CYP1A2. Hitherto, the effects of caffeine on Clozapine levels have always been modest, as have the clinical manifestations of toxicity resulting from their interaction. We present a case of severe toxicity as...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043221/ https://www.ncbi.nlm.nih.gov/pubmed/33849480 http://dx.doi.org/10.1186/s12888-021-03199-x |