Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signature

Cutaneous leishmaniasis is a localized infection controlled by CD4+ T cells that produce IFN-γ within lesions. Phagocytic cells recruited to lesions, such as monocytes, are then exposed to IFN-γ which triggers their ability to kill the intracellular parasites. Consistent with this, transcriptional a...

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Detalles Bibliográficos
Autores principales: Farias Amorim, Camila, O. Novais, Fernanda, Nguyen, Ba T., Nascimento, Mauricio T., Lago, Jamile, Lago, Alexsandro S., Carvalho, Lucas P., Beiting, Daniel P., Scott, Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043375/
https://www.ncbi.nlm.nih.gov/pubmed/33793565
http://dx.doi.org/10.1371/journal.pntd.0009321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043375/
https://www.ncbi.nlm.nih.gov/pubmed/33793565
http://dx.doi.org/10.1371/journal.pntd.0009321

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