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Breast lesion detection through MammoWave device: Empirical detection capability assessment of microwave images’ parameters
MammoWave is a microwave imaging device for breast lesions detection, which operates using two (azimuthally rotating) antennas without any matching liquid. Images, subsequently obtained by resorting to Huygens Principle, are intensity maps, representing the homogeneity of tissues’ dielectric propert...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043413/ https://www.ncbi.nlm.nih.gov/pubmed/33848318 http://dx.doi.org/10.1371/journal.pone.0250005 |
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author | Sani, Lorenzo Vispa, Alessandro Loretoni, Riccardo Duranti, Michele Ghavami, Navid Alvarez Sánchez-Bayuela, Daniel Caschera, Stefano Paoli, Martina Bigotti, Alessandra Badia, Mario Scorsipa, Michele Raspa, Giovanni Ghavami, Mohammad Tiberi, Gianluigi |
author_facet | Sani, Lorenzo Vispa, Alessandro Loretoni, Riccardo Duranti, Michele Ghavami, Navid Alvarez Sánchez-Bayuela, Daniel Caschera, Stefano Paoli, Martina Bigotti, Alessandra Badia, Mario Scorsipa, Michele Raspa, Giovanni Ghavami, Mohammad Tiberi, Gianluigi |
author_sort | Sani, Lorenzo |
collection | PubMed |
description | MammoWave is a microwave imaging device for breast lesions detection, which operates using two (azimuthally rotating) antennas without any matching liquid. Images, subsequently obtained by resorting to Huygens Principle, are intensity maps, representing the homogeneity of tissues’ dielectric properties. In this paper, we propose to generate, for each breast, a set of conductivity weighted microwave images by using different values of conductivity in the Huygens Principle imaging algorithm. Next, microwave images’ parameters, i.e. features, are introduced to quantify the non-homogenous behaviour of the image. We empirically verify on 103 breasts that a selection of these features may allow distinction between breasts with no radiological finding (NF) and breasts with radiological findings (WF), i.e. with lesions which may be benign or malignant. Statistical significance was set at p<0.05. We obtained single features Area Under the receiver operating characteristic Curves (AUCs) spanning from 0.65 to 0.69. In addition, an empirical rule-of-thumb allowing breast assessment is introduced using a binary score S operating on an appropriate combination of features. Performances of such rule-of-thumb are evaluated empirically, obtaining a sensitivity of 74%, which increases to 82% when considering dense breasts only. |
format | Online Article Text |
id | pubmed-8043413 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-80434132021-04-21 Breast lesion detection through MammoWave device: Empirical detection capability assessment of microwave images’ parameters Sani, Lorenzo Vispa, Alessandro Loretoni, Riccardo Duranti, Michele Ghavami, Navid Alvarez Sánchez-Bayuela, Daniel Caschera, Stefano Paoli, Martina Bigotti, Alessandra Badia, Mario Scorsipa, Michele Raspa, Giovanni Ghavami, Mohammad Tiberi, Gianluigi PLoS One Research Article MammoWave is a microwave imaging device for breast lesions detection, which operates using two (azimuthally rotating) antennas without any matching liquid. Images, subsequently obtained by resorting to Huygens Principle, are intensity maps, representing the homogeneity of tissues’ dielectric properties. In this paper, we propose to generate, for each breast, a set of conductivity weighted microwave images by using different values of conductivity in the Huygens Principle imaging algorithm. Next, microwave images’ parameters, i.e. features, are introduced to quantify the non-homogenous behaviour of the image. We empirically verify on 103 breasts that a selection of these features may allow distinction between breasts with no radiological finding (NF) and breasts with radiological findings (WF), i.e. with lesions which may be benign or malignant. Statistical significance was set at p<0.05. We obtained single features Area Under the receiver operating characteristic Curves (AUCs) spanning from 0.65 to 0.69. In addition, an empirical rule-of-thumb allowing breast assessment is introduced using a binary score S operating on an appropriate combination of features. Performances of such rule-of-thumb are evaluated empirically, obtaining a sensitivity of 74%, which increases to 82% when considering dense breasts only. Public Library of Science 2021-04-13 /pmc/articles/PMC8043413/ /pubmed/33848318 http://dx.doi.org/10.1371/journal.pone.0250005 Text en © 2021 Sani et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Sani, Lorenzo Vispa, Alessandro Loretoni, Riccardo Duranti, Michele Ghavami, Navid Alvarez Sánchez-Bayuela, Daniel Caschera, Stefano Paoli, Martina Bigotti, Alessandra Badia, Mario Scorsipa, Michele Raspa, Giovanni Ghavami, Mohammad Tiberi, Gianluigi Breast lesion detection through MammoWave device: Empirical detection capability assessment of microwave images’ parameters |
title | Breast lesion detection through MammoWave device: Empirical detection capability assessment of microwave images’ parameters |
title_full | Breast lesion detection through MammoWave device: Empirical detection capability assessment of microwave images’ parameters |
title_fullStr | Breast lesion detection through MammoWave device: Empirical detection capability assessment of microwave images’ parameters |
title_full_unstemmed | Breast lesion detection through MammoWave device: Empirical detection capability assessment of microwave images’ parameters |
title_short | Breast lesion detection through MammoWave device: Empirical detection capability assessment of microwave images’ parameters |
title_sort | breast lesion detection through mammowave device: empirical detection capability assessment of microwave images’ parameters |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043413/ https://www.ncbi.nlm.nih.gov/pubmed/33848318 http://dx.doi.org/10.1371/journal.pone.0250005 |
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