Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality

The ongoing evolution of SARS-CoV-2 into more easily transmissible and infectious variants has sparked concern over the continued effectiveness of existing therapeutic antibodies and vaccines. Hence, together with increased genomic surveillance, methods to rapidly develop and assess effective interv...

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Detalles Bibliográficos
Autores principales: Goike, Jule, Hsieh, Ching-Lin, Horton, Andrew, Gardner, Elizabeth C., Bartzoka, Foteini, Wang, Nianshuang, Javanmardi, Kamyab, Herbert, Andrew, Abbassi, Shawn, Renberg, Rebecca, Johanson, Michael J., Cardona, Jose A., Segall-Shapiro, Thomas, Zhou, Ling, Nissly, Ruth H., Gontu, Abhinay, Byrom, Michelle, Maranhao, Andre C., Battenhouse, Anna M., Gejji, Varun, Soto-Sierra, Laura, Foster, Emma R., Woodard, Susan L., Nikolov, Zivko L., Lavinder, Jason, Voss, Will N., Annapareddy, Ankur, Ippolito, Gregory C., Ellington, Andrew D., Marcotte, Edward M., Finkelstein, Ilya J., Hughes, Randall A., Musser, James M., Kuchipudi, Suresh V., Kapur, Vivek, Georgiou, George, Dye, John M., Boutz, Daniel R., McLellan, Jason S., Gollihar, Jimmy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043448/
https://www.ncbi.nlm.nih.gov/pubmed/33851158
http://dx.doi.org/10.1101/2021.04.07.438849

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