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Development of a Novel Human CD147 Transgenic NSG Mouse Model to test SARS-CoV-2 Infection and Immune Responses

An animal model that can mimic the SARS-CoV-2 infection in humans is critical to understanding the newly emerged, rapidly spreading SARS-CoV-2 and development of therapeutic strategies. Studies show that the spike (S) proteins of SARS-CoV (SARS-CoV-S-1-S) and SARS-CoV-2 (SARS-CoV-2-S) bind to human...

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Detalles Bibliográficos
Autores principales:	Badeti, Saiaditya, Tseng, Hsiang-chi, Romanienko, Peter, Yehia, Ghassan, Liu, Dongfang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043462/ https://www.ncbi.nlm.nih.gov/pubmed/33851148 http://dx.doi.org/10.21203/rs.3.rs-396257/v1

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