Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients

This brief report presents a series of 5 pregnant women treated for rifampicin-resistant tuberculosis with the novel drugs bedaquiline, delamanid, and linezolid as part of an optimized backbone regimen and reviews the outcomes of the children born to them. Although the case series is small, all chil...

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Detalles Bibliográficos
Autores principales: Acquah, Rebecca, Mohr-Holland, Erika, Daniels, Johnny, Furin, Jennifer, Loveday, Marian, Mudaly, Vanessa, Reuter, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Maternal-Neonatal Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043512/
https://www.ncbi.nlm.nih.gov/pubmed/33847295
http://dx.doi.org/10.1097/INF.0000000000003069
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author Acquah, Rebecca
Mohr-Holland, Erika
Daniels, Johnny
Furin, Jennifer
Loveday, Marian
Mudaly, Vanessa
Reuter, Anja
author_facet Acquah, Rebecca
Mohr-Holland, Erika
Daniels, Johnny
Furin, Jennifer
Loveday, Marian
Mudaly, Vanessa
Reuter, Anja
author_sort Acquah, Rebecca
collection PubMed
description This brief report presents a series of 5 pregnant women treated for rifampicin-resistant tuberculosis with the novel drugs bedaquiline, delamanid, and linezolid as part of an optimized backbone regimen and reviews the outcomes of the children born to them. Although the case series is small, all children had excellent birth outcomes suggesting pregnant women should not be denied access to novel therapies for RR-TB.
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spelling pubmed-80435122021-04-19 Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients Acquah, Rebecca Mohr-Holland, Erika Daniels, Johnny Furin, Jennifer Loveday, Marian Mudaly, Vanessa Reuter, Anja Pediatr Infect Dis J Maternal-Neonatal Reports This brief report presents a series of 5 pregnant women treated for rifampicin-resistant tuberculosis with the novel drugs bedaquiline, delamanid, and linezolid as part of an optimized backbone regimen and reviews the outcomes of the children born to them. Although the case series is small, all children had excellent birth outcomes suggesting pregnant women should not be denied access to novel therapies for RR-TB. Lippincott Williams & Wilkins 2021-02-02 2021-05 /pmc/articles/PMC8043512/ /pubmed/33847295 http://dx.doi.org/10.1097/INF.0000000000003069 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Maternal-Neonatal Reports
Acquah, Rebecca
Mohr-Holland, Erika
Daniels, Johnny
Furin, Jennifer
Loveday, Marian
Mudaly, Vanessa
Reuter, Anja
Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients
title Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients
title_full Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients
title_fullStr Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients
title_full_unstemmed Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients
title_short Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients
title_sort outcomes of children born to pregnant women with drug-resistant tuberculosis treated with novel drugs in khayelitsha, south africa: a report of five patients
topic Maternal-Neonatal Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043512/
https://www.ncbi.nlm.nih.gov/pubmed/33847295
http://dx.doi.org/10.1097/INF.0000000000003069
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