A rare case of eptifibatide-induced thrombocytopenia

Eptifibatide is a glycoprotein (GP) IIb/IIIa receptor antagonist, used for the treatment of acute coronary syndrome with high-risk features or ongoing ischemia. Several case reports have described thrombocytopenia as a rare side effect of eptifibatide administration. The exact mechanism remains uncl...

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Autores principales: Kamar, Khalil, MacDougall, Kira, Alsheikh, Mira, Parylo, Sara, Skaradinskiy, Yevgeniy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043518/
https://www.ncbi.nlm.nih.gov/pubmed/33889336
http://dx.doi.org/10.1080/20009666.2021.1871802
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author Kamar, Khalil
MacDougall, Kira
Alsheikh, Mira
Parylo, Sara
Skaradinskiy, Yevgeniy
author_facet Kamar, Khalil
MacDougall, Kira
Alsheikh, Mira
Parylo, Sara
Skaradinskiy, Yevgeniy
author_sort Kamar, Khalil
collection PubMed
description Eptifibatide is a glycoprotein (GP) IIb/IIIa receptor antagonist, used for the treatment of acute coronary syndrome with high-risk features or ongoing ischemia. Several case reports have described thrombocytopenia as a rare side effect of eptifibatide administration. The exact mechanism remains unclear but may be due to immune destruction of circulating platelets in the peripheral blood. We present the case of acute-onset severe thrombocytopenia in a 76-year-old female undergoing percutaneous coronary intervention.
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spelling pubmed-80435182021-04-21 A rare case of eptifibatide-induced thrombocytopenia Kamar, Khalil MacDougall, Kira Alsheikh, Mira Parylo, Sara Skaradinskiy, Yevgeniy J Community Hosp Intern Med Perspect Case Report Eptifibatide is a glycoprotein (GP) IIb/IIIa receptor antagonist, used for the treatment of acute coronary syndrome with high-risk features or ongoing ischemia. Several case reports have described thrombocytopenia as a rare side effect of eptifibatide administration. The exact mechanism remains unclear but may be due to immune destruction of circulating platelets in the peripheral blood. We present the case of acute-onset severe thrombocytopenia in a 76-year-old female undergoing percutaneous coronary intervention. Taylor & Francis 2021-03-23 /pmc/articles/PMC8043518/ /pubmed/33889336 http://dx.doi.org/10.1080/20009666.2021.1871802 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of Greater Baltimore Medical Center. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kamar, Khalil
MacDougall, Kira
Alsheikh, Mira
Parylo, Sara
Skaradinskiy, Yevgeniy
A rare case of eptifibatide-induced thrombocytopenia
title A rare case of eptifibatide-induced thrombocytopenia
title_full A rare case of eptifibatide-induced thrombocytopenia
title_fullStr A rare case of eptifibatide-induced thrombocytopenia
title_full_unstemmed A rare case of eptifibatide-induced thrombocytopenia
title_short A rare case of eptifibatide-induced thrombocytopenia
title_sort rare case of eptifibatide-induced thrombocytopenia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043518/
https://www.ncbi.nlm.nih.gov/pubmed/33889336
http://dx.doi.org/10.1080/20009666.2021.1871802
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