Cargando…

Functional landscape of SARS-CoV-2 cellular restriction

A deficient interferon (IFN) response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been implicated as a determinant of severe coronavirus disease 2019 (COVID-19). To identify the molecular effectors that govern IFN control of SARS-CoV-2 infection, we conducted a larg...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin-Sancho, Laura, Lewinski, Mary K., Pache, Lars, Stoneham, Charlotte A., Yin, Xin, Becker, Mark E., Pratt, Dexter, Churas, Christopher, Rosenthal, Sara B., Liu, Sophie, Weston, Stuart, De Jesus, Paul D., O’Neill, Alan M., Gounder, Anshu P., Nguyen, Courtney, Pu, Yuan, Curry, Heather M., Oom, Aaron L., Miorin, Lisa, Rodriguez-Frandsen, Ariel, Zheng, Fan, Wu, Chunxiang, Xiong, Yong, Urbanowski, Matthew, Shaw, Megan L., Chang, Max W., Benner, Christopher, Hope, Thomas J., Frieman, Matthew B., García-Sastre, Adolfo, Ideker, Trey, Hultquist, Judd F., Guatelli, John, Chanda, Sumit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043580/
https://www.ncbi.nlm.nih.gov/pubmed/33930332
http://dx.doi.org/10.1016/j.molcel.2021.04.008