A 3-Case Series of Autoimmune Haemolytic Anaemia and COVID-19: Is Plasma Exchange an Alternative?

COVID-19 has rarely been associated with immune-mediated phenomena such as autoimmune haemolytic anaemia (AIHA). Both cold hemolysis with cold agglutinin detection and warm haemolysis have been described with variable prognoses. Current treatment regimens are based on experience with other case seri...

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Autores principales: Ramos-Ruperto, L., García-Pérez, Eduardo, Hernández-Maraver, D., Kerguelén-Fuentes, A., Viejo-Llorente, A., Robles-Marhuenda, Á., Busca-Arenzana, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Covid-19
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043757/
https://www.ncbi.nlm.nih.gov/pubmed/33870092
http://dx.doi.org/10.1007/s42399-021-00884-6
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author Ramos-Ruperto, L.
García-Pérez, Eduardo
Hernández-Maraver, D.
Kerguelén-Fuentes, A.
Viejo-Llorente, A.
Robles-Marhuenda, Á.
Busca-Arenzana, C.
author_facet Ramos-Ruperto, L.
García-Pérez, Eduardo
Hernández-Maraver, D.
Kerguelén-Fuentes, A.
Viejo-Llorente, A.
Robles-Marhuenda, Á.
Busca-Arenzana, C.
author_sort Ramos-Ruperto, L.
collection PubMed
description COVID-19 has rarely been associated with immune-mediated phenomena such as autoimmune haemolytic anaemia (AIHA). Both cold hemolysis with cold agglutinin detection and warm haemolysis have been described with variable prognoses. Current treatment regimens are based on experience with other case series and case reports, which still represent a clinical challenge. Corticosteroids, red cell transfusions and rituximab have been successfully employed. We present 3 cases of AIHA in the context of COVID-19 disease, the first case successfully treated with plasma exchange and long-term follow-up of the 3 cases showing complete remission of anaemia.
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spelling pubmed-80437572021-04-14 A 3-Case Series of Autoimmune Haemolytic Anaemia and COVID-19: Is Plasma Exchange an Alternative? Ramos-Ruperto, L. García-Pérez, Eduardo Hernández-Maraver, D. Kerguelén-Fuentes, A. Viejo-Llorente, A. Robles-Marhuenda, Á. Busca-Arenzana, C. SN Compr Clin Med Covid-19 COVID-19 has rarely been associated with immune-mediated phenomena such as autoimmune haemolytic anaemia (AIHA). Both cold hemolysis with cold agglutinin detection and warm haemolysis have been described with variable prognoses. Current treatment regimens are based on experience with other case series and case reports, which still represent a clinical challenge. Corticosteroids, red cell transfusions and rituximab have been successfully employed. We present 3 cases of AIHA in the context of COVID-19 disease, the first case successfully treated with plasma exchange and long-term follow-up of the 3 cases showing complete remission of anaemia. Springer International Publishing 2021-04-14 2021 /pmc/articles/PMC8043757/ /pubmed/33870092 http://dx.doi.org/10.1007/s42399-021-00884-6 Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Covid-19
Ramos-Ruperto, L.
García-Pérez, Eduardo
Hernández-Maraver, D.
Kerguelén-Fuentes, A.
Viejo-Llorente, A.
Robles-Marhuenda, Á.
Busca-Arenzana, C.
A 3-Case Series of Autoimmune Haemolytic Anaemia and COVID-19: Is Plasma Exchange an Alternative?
title A 3-Case Series of Autoimmune Haemolytic Anaemia and COVID-19: Is Plasma Exchange an Alternative?
title_full A 3-Case Series of Autoimmune Haemolytic Anaemia and COVID-19: Is Plasma Exchange an Alternative?
title_fullStr A 3-Case Series of Autoimmune Haemolytic Anaemia and COVID-19: Is Plasma Exchange an Alternative?
title_full_unstemmed A 3-Case Series of Autoimmune Haemolytic Anaemia and COVID-19: Is Plasma Exchange an Alternative?
title_short A 3-Case Series of Autoimmune Haemolytic Anaemia and COVID-19: Is Plasma Exchange an Alternative?
title_sort 3-case series of autoimmune haemolytic anaemia and covid-19: is plasma exchange an alternative?
topic Covid-19
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043757/
https://www.ncbi.nlm.nih.gov/pubmed/33870092
http://dx.doi.org/10.1007/s42399-021-00884-6
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