Cargando…

CYP2C9*3/*3 Gene Expression Affects the Total and Free Concentrations of Valproic Acid in Pediatric Patients with Epilepsy

PURPOSE: To perform therapeutic drug monitoring (TDM) of total and free plasma valproic acid (VPA) concentrations in pediatric patients with epilepsy and to analyze related factors. PATIENTS AND METHODS: Pediatric epileptic patients treated in 2015–2019 in our hospital were assessed. Total and free...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Xikun, Dong, Weichong, Li, Haoran, Yang, Xiuling, Jin, Yiran, Zhang, Zhiqing, Jiang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043849/
https://www.ncbi.nlm.nih.gov/pubmed/33859491
http://dx.doi.org/10.2147/PGPM.S301893