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Orbitadekompression bei endokriner Orbitopathie – Erfahrungen und Ergebnisse

BACKGROUND: Graves’ orbitopathy is the most frequent extrathyroidal manifestation of Gravesʼ disease, affecting approximately 25–50% of patients. It leads to inflammation and swelling of orbital soft tissues. The treatment is mostly conservative. Surgical orbital decompression is indicated in severe...

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Autores principales: Küchlin, Sebastian, Gruber, Markus, Reich, Michael, Joachimsen, Lutz, Metzger, Marc, Beck, Jürgen, Grauvogel, Jürgen, Lagrèze, Wolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043865/
https://www.ncbi.nlm.nih.gov/pubmed/32681301
http://dx.doi.org/10.1007/s00347-020-01181-8
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author Küchlin, Sebastian
Gruber, Markus
Reich, Michael
Joachimsen, Lutz
Metzger, Marc
Beck, Jürgen
Grauvogel, Jürgen
Lagrèze, Wolf A.
author_facet Küchlin, Sebastian
Gruber, Markus
Reich, Michael
Joachimsen, Lutz
Metzger, Marc
Beck, Jürgen
Grauvogel, Jürgen
Lagrèze, Wolf A.
author_sort Küchlin, Sebastian
collection PubMed
description BACKGROUND: Graves’ orbitopathy is the most frequent extrathyroidal manifestation of Gravesʼ disease, affecting approximately 25–50% of patients. It leads to inflammation and swelling of orbital soft tissues. The treatment is mostly conservative. Surgical orbital decompression is indicated in severe cases with disfiguring exophthalmos or an acute steroid-refractive threat to vision, facilitating visual and cosmetic recovery. An important aspect in the quality of care is the avoidance of postoperative diplopia. OBJECTIVE: To report experiences and results from 100 cases of orbital decompression surgery performed on 62 patients at a multidisciplinary orbit center. Patients with signs of apical crowding were treated by pterional decompression. Patients without signs of apical crowding were treated either by deep lateral wall resection or pterional decompression. METHODS: A retrospective data analysis was carried out. RESULTS: The mean reduction in exophthalmos was 2.9 mm. Visual acuity improved by a mean of 2.2 lines in eyes with sight-threatening disease. In moderate to severe disease, visual acuity remained stable. The complication rate was 4%. New postoperative diplopia occurred after two interventions and one patient experienced a deterioration in visual acuity from 0.8 to 0.1. In nine cases, surgery led to a complete regression of previously reported double vision. CONCLUSION: Visual acuity gain, reduction of exophthalmos and complications in this collective are comparable to previously published results. The results of this study confirm the role of orbital decompression in the treatment of sight-threatening and severely disfiguring endocrine orbitopathy.
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spelling pubmed-80438652021-04-27 Orbitadekompression bei endokriner Orbitopathie – Erfahrungen und Ergebnisse Küchlin, Sebastian Gruber, Markus Reich, Michael Joachimsen, Lutz Metzger, Marc Beck, Jürgen Grauvogel, Jürgen Lagrèze, Wolf A. Ophthalmologe Originalien BACKGROUND: Graves’ orbitopathy is the most frequent extrathyroidal manifestation of Gravesʼ disease, affecting approximately 25–50% of patients. It leads to inflammation and swelling of orbital soft tissues. The treatment is mostly conservative. Surgical orbital decompression is indicated in severe cases with disfiguring exophthalmos or an acute steroid-refractive threat to vision, facilitating visual and cosmetic recovery. An important aspect in the quality of care is the avoidance of postoperative diplopia. OBJECTIVE: To report experiences and results from 100 cases of orbital decompression surgery performed on 62 patients at a multidisciplinary orbit center. Patients with signs of apical crowding were treated by pterional decompression. Patients without signs of apical crowding were treated either by deep lateral wall resection or pterional decompression. METHODS: A retrospective data analysis was carried out. RESULTS: The mean reduction in exophthalmos was 2.9 mm. Visual acuity improved by a mean of 2.2 lines in eyes with sight-threatening disease. In moderate to severe disease, visual acuity remained stable. The complication rate was 4%. New postoperative diplopia occurred after two interventions and one patient experienced a deterioration in visual acuity from 0.8 to 0.1. In nine cases, surgery led to a complete regression of previously reported double vision. CONCLUSION: Visual acuity gain, reduction of exophthalmos and complications in this collective are comparable to previously published results. The results of this study confirm the role of orbital decompression in the treatment of sight-threatening and severely disfiguring endocrine orbitopathy. Springer Medizin 2020-07-17 2021 /pmc/articles/PMC8043865/ /pubmed/32681301 http://dx.doi.org/10.1007/s00347-020-01181-8 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open Access. Dieser Artikel wird unter der Creative Commons Namensnennung 4.0 International Lizenz veröffentlicht, welche die Nutzung, Vervielfältigung, Bearbeitung, Verbreitung und Wiedergabe in jeglichem Medium und Format erlaubt, sofern Sie den/die ursprünglichen Autor(en) und die Quelle ordnungsgemäß nennen, einen Link zur Creative Commons Lizenz beifügen und angeben, ob Änderungen vorgenommen wurden. Die in diesem Artikel enthaltenen Bilder und sonstiges Drittmaterial unterliegen ebenfalls der genannten Creative Commons Lizenz, sofern sich aus der Abbildungslegende nichts anderes ergibt. Sofern das betreffende Material nicht unter der genannten Creative Commons Lizenz steht und die betreffende Handlung nicht nach gesetzlichen Vorschriften erlaubt ist, ist für die oben aufgeführten Weiterverwendungen des Materials die Einwilligung des jeweiligen Rechteinhabers einzuholen. Weitere Details zur Lizenz entnehmen Sie bitte der Lizenzinformation auf http://creativecommons.org/licenses/by/4.0/deed.de (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Originalien
Küchlin, Sebastian
Gruber, Markus
Reich, Michael
Joachimsen, Lutz
Metzger, Marc
Beck, Jürgen
Grauvogel, Jürgen
Lagrèze, Wolf A.
Orbitadekompression bei endokriner Orbitopathie – Erfahrungen und Ergebnisse
title Orbitadekompression bei endokriner Orbitopathie – Erfahrungen und Ergebnisse
title_full Orbitadekompression bei endokriner Orbitopathie – Erfahrungen und Ergebnisse
title_fullStr Orbitadekompression bei endokriner Orbitopathie – Erfahrungen und Ergebnisse
title_full_unstemmed Orbitadekompression bei endokriner Orbitopathie – Erfahrungen und Ergebnisse
title_short Orbitadekompression bei endokriner Orbitopathie – Erfahrungen und Ergebnisse
title_sort orbitadekompression bei endokriner orbitopathie – erfahrungen und ergebnisse
topic Originalien
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043865/
https://www.ncbi.nlm.nih.gov/pubmed/32681301
http://dx.doi.org/10.1007/s00347-020-01181-8
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