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Development of a chiral HPLC method for the separation and quantification of hydroxychloroquine enantiomers

Hydroxychloroquine (2-[[4-[(7-Chloroquinolin-4-yl) amino]pentyl](ethyl) amino]-ethanol, HCQ), an effective anti-malarial drug, has been tested in the clinics for potential treatment of severe coronavirus disease 2019 (COVID-19). Despite the controversy around the clinical benefits of HCQ, the existe...

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Detalles Bibliográficos
Autores principales:	Xiong, Xisheng, Wang, Kun, Tang, Tao, Fang, Jinzhi, Chen, Yijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044086/ https://www.ncbi.nlm.nih.gov/pubmed/33850241 http://dx.doi.org/10.1038/s41598-021-87511-5

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