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Synaptic AP2 CCV life cycle regulation by the Eps15, ITSN1, Sgip1/AP2, synaptojanin1 interactome

The AP1/σ1B knockout causes impaired synaptic vesicle recycling and enhanced protein sorting into endosomes, leading to severe intellectual disability. These disturbances in synaptic protein sorting induce as a secondary phenotype the upregulation of AP2 CCV mediated endocytosis. Synapses contain ca...

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Detalles Bibliográficos
Autores principales:	Mishra, R., Sengül, G. F., Candiello, E., Schu, P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044098/ https://www.ncbi.nlm.nih.gov/pubmed/33850201 http://dx.doi.org/10.1038/s41598-021-87591-3

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