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Investigations on the potential of optical coherence tomography as an imaging tool for eustachian tube

The purpose of this study was to explore the feasibility of eustachian tube optical coherence tomography (ET-OCT) for imaging the pharyngeal region of the eustachian tube (ET). Ten subjects with ear complaints underwent ET-OCT guided by nasal endoscopy, and ET-OCT examination was performed on both s...

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Autores principales: Sun, Xiao-Mei, Luo, Jia-Qi, Xiao, Zhi-Wen, Gu, Qing-Yu, Lan, Lin-Chan, Zhang, Hui-Qing, Zhang, Guan-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044113/
https://www.ncbi.nlm.nih.gov/pubmed/33850252
http://dx.doi.org/10.1038/s41598-021-87637-6
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author Sun, Xiao-Mei
Luo, Jia-Qi
Xiao, Zhi-Wen
Gu, Qing-Yu
Lan, Lin-Chan
Zhang, Hui-Qing
Zhang, Guan-Ping
author_facet Sun, Xiao-Mei
Luo, Jia-Qi
Xiao, Zhi-Wen
Gu, Qing-Yu
Lan, Lin-Chan
Zhang, Hui-Qing
Zhang, Guan-Ping
author_sort Sun, Xiao-Mei
collection PubMed
description The purpose of this study was to explore the feasibility of eustachian tube optical coherence tomography (ET-OCT) for imaging the pharyngeal region of the eustachian tube (ET). Ten subjects with ear complaints underwent ET-OCT guided by nasal endoscopy, and ET-OCT examination was performed on both sides of each subject's ETs. The process and resulting images were analysed. Ten subjects ranging from 21 to 73 years old (45 ± 14.77) were enrolled in this study. Eighteen ET-OCT imaging examinations were completed. The mean duration of each examination was 2.80 ± 1.62 min (ranging from 2 to 7 min). There were no adverse events or complications. In some subjects, the ET-OCT images clearly presented the microstructures of the ET wall, including the lumen, mucosa, submucosa, cartilage and plica. However, in some subjects, it showed different characteristics, such as an unclear hierarchy and secretions in the lumen. ET-OCT may help to distinguish the structural composition of the ET and elucidate related pathophysiological mechanisms. It is a valuable imaging tool suited for the ET, with potential diagnostic value in determining the morphology of the lumen, intraluminal mucosa and submucosal tissue in the pharyngeal region of the ET.
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spelling pubmed-80441132021-04-14 Investigations on the potential of optical coherence tomography as an imaging tool for eustachian tube Sun, Xiao-Mei Luo, Jia-Qi Xiao, Zhi-Wen Gu, Qing-Yu Lan, Lin-Chan Zhang, Hui-Qing Zhang, Guan-Ping Sci Rep Article The purpose of this study was to explore the feasibility of eustachian tube optical coherence tomography (ET-OCT) for imaging the pharyngeal region of the eustachian tube (ET). Ten subjects with ear complaints underwent ET-OCT guided by nasal endoscopy, and ET-OCT examination was performed on both sides of each subject's ETs. The process and resulting images were analysed. Ten subjects ranging from 21 to 73 years old (45 ± 14.77) were enrolled in this study. Eighteen ET-OCT imaging examinations were completed. The mean duration of each examination was 2.80 ± 1.62 min (ranging from 2 to 7 min). There were no adverse events or complications. In some subjects, the ET-OCT images clearly presented the microstructures of the ET wall, including the lumen, mucosa, submucosa, cartilage and plica. However, in some subjects, it showed different characteristics, such as an unclear hierarchy and secretions in the lumen. ET-OCT may help to distinguish the structural composition of the ET and elucidate related pathophysiological mechanisms. It is a valuable imaging tool suited for the ET, with potential diagnostic value in determining the morphology of the lumen, intraluminal mucosa and submucosal tissue in the pharyngeal region of the ET. Nature Publishing Group UK 2021-04-13 /pmc/articles/PMC8044113/ /pubmed/33850252 http://dx.doi.org/10.1038/s41598-021-87637-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Sun, Xiao-Mei
Luo, Jia-Qi
Xiao, Zhi-Wen
Gu, Qing-Yu
Lan, Lin-Chan
Zhang, Hui-Qing
Zhang, Guan-Ping
Investigations on the potential of optical coherence tomography as an imaging tool for eustachian tube
title Investigations on the potential of optical coherence tomography as an imaging tool for eustachian tube
title_full Investigations on the potential of optical coherence tomography as an imaging tool for eustachian tube
title_fullStr Investigations on the potential of optical coherence tomography as an imaging tool for eustachian tube
title_full_unstemmed Investigations on the potential of optical coherence tomography as an imaging tool for eustachian tube
title_short Investigations on the potential of optical coherence tomography as an imaging tool for eustachian tube
title_sort investigations on the potential of optical coherence tomography as an imaging tool for eustachian tube
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044113/
https://www.ncbi.nlm.nih.gov/pubmed/33850252
http://dx.doi.org/10.1038/s41598-021-87637-6
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