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Influence of xanthine oxidoreductase inhibitor, topiroxostat, on body weight of diabetic obese mice

Plasma xanthine oxidoreductase (XOR) activity is high in metabolic disorders such as diabetic mellitus, obesity, or overweight. Thus, this study investigated whether the XOR inhibitor, topiroxostat, affected body weight. Male db/db mice were fed standard diets with or without topiroxostat for 4 week...

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Detalles Bibliográficos
Autores principales: Nakamura, Takashi, Nampei, Mai, Murase, Takayo, Satoh, Etsuko, Akari, Seigo, Katoh, Noriaki, Mizukami, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044114/
https://www.ncbi.nlm.nih.gov/pubmed/33850106
http://dx.doi.org/10.1038/s41387-021-00155-2

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