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Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney

The integration of single cell transcriptome and chromatin accessibility datasets enables a deeper understanding of cell heterogeneity. We performed single nucleus ATAC (snATAC-seq) and RNA (snRNA-seq) sequencing to generate paired, cell-type-specific chromatin accessibility and transcriptional prof...

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Detalles Bibliográficos
Autores principales:	Muto, Yoshiharu, Wilson, Parker C., Ledru, Nicolas, Wu, Haojia, Dimke, Henrik, Waikar, Sushrut S., Humphreys, Benjamin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044133/ https://www.ncbi.nlm.nih.gov/pubmed/33850129 http://dx.doi.org/10.1038/s41467-021-22368-w

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