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B1a and B2 cells are characterized by distinct CpG modification states at DNMT3A-maintained enhancers

The B1 and B2 lineages of B cells contribute to protection from pathogens in distinct ways. The role of the DNA CpG methylome in specifying these two B-cell fates is still unclear. Here we profile the CpG modifications and transcriptomes of peritoneal B1a and follicular B2 cells, as well as their re...

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Detalles Bibliográficos
Autores principales:	Mahajan, Vinay S., Mattoo, Hamid, Sun, Na, Viswanadham, Vinayak, Yuen, Grace J., Allard-Chamard, Hugues, Ahmad, Maimuna, Murphy, Samuel J. H., Cariappa, Annaiah, Tuncay, Yesim, Pillai, Shiv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044213/ https://www.ncbi.nlm.nih.gov/pubmed/33850140 http://dx.doi.org/10.1038/s41467-021-22458-9

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