Cargando…

PTBP1 is necessary for dendritic cells to regulate T‐cell homeostasis and antitumour immunity

Dendritic cells (DCs) play an important role in linking innate and adaptive immunity. DCs can sense endogenous and exogenous antigens and present those antigens to T cells to induce an immune response or immune tolerance. During activation, alternative splicing (AS) in DCs is dramatically changed to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geng, Guangfeng, Xu, Changlu, Peng, Nan, Li, Yue, Liu, Jinhua, Wu, Jing, Liang, Jing, Zhu, Yushan, Shi, Lihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044338/ https://www.ncbi.nlm.nih.gov/pubmed/33421118 http://dx.doi.org/10.1111/imm.13304

Ejemplares similares

The RNA binding protein PTBP1 is necessary for B cell selection in germinal centers
por: Monzón-Casanova, Elisa, et al.
Publicado: (2018)

PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells
por: Guo, Jihua, et al.
Publicado: (2015)

Receptor-mediated mitophagy regulates EPO production and protects against renal anemia
por: Geng, Guangfeng, et al.
Publicado: (2021)

Control of T(reg) cell homeostasis and immune equilibrium by Lkb1 in dendritic cells
por: Chen, Song, et al.
Publicado: (2018)

Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells
por: Zhao, Yinghua, et al.
Publicado: (2016)

Targeting cancer-associated fibroblast-secreted WNT2 restores dendritic cell-mediated antitumour immunity
por: Huang, Tu-Xiong, et al.
Publicado: (2022)

A Novel In Situ Dendritic Cell Vaccine Triggered by Rose Bengal Enhances Adaptive Antitumour Immunity
por: Zhang, Lanlin, et al.
Publicado: (2022)

Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
por: Sioud, Mouldy, et al.
Publicado: (2016)

Anti-CD40-induced inflammatory E-cadherin+ dendritic cells enhance T cell responses and antitumour immunity in murine Lewis lung carcinoma
por: Zhang, Yong, et al.
Publicado: (2015)

Blockade of MIF–CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma
por: Figueiredo, Carlos R., et al.
Publicado: (2018)

Myosin Light-Chain Kinase Is Necessary for Membrane Homeostasis in Cochlear Inner Hair Cells
por: Zhu, Guang-Jie, et al.
Publicado: (2012)

Apoptotic Cells Induced Signaling for Immune Homeostasis in Macrophages and Dendritic Cells
por: Trahtemberg, Uriel, et al.
Publicado: (2017)

Psd-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2
por: Zheng, Sika, et al.
Publicado: (2012)

Multiple determinants of splicing repression activity in the polypyrimidine tract binding proteins, PTBP1 and PTBP2
por: Keppetipola, Niroshika M., et al.
Publicado: (2016)

Metabolic programming in dendritic cells tailors immune responses and homeostasis
por: Møller, Sofie Hedlund, et al.
Publicado: (2021)

Conventional Type 1 Dendritic Cells in Intestinal Immune Homeostasis
por: Sasaki, Izumi, et al.
Publicado: (2022)

Polypyrimidine tract binding proteins PTBP1 and PTBP2 interact with distinct proteins under splicing conditions
por: Pina, Jeffrey M., et al.
Publicado: (2022)

The MicroRNA-106a/20b Strongly Enhances the Antitumour Immune Responses of Dendritic Cells Pulsed with Glioma Stem Cells by Targeting STAT3
por: Zhou, Hui, et al.
Publicado: (2022)

Tropomodulin1 Expression Increases Upon Maturation in Dendritic Cells and Promotes Their Maturation and Immune Functions
por: Liu, Xianmei, et al.
Publicado: (2021)

NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis
por: Jie, Zuliang, et al.
Publicado: (2018)

Antitumour Antibiotics
por: Fox, B. W.
Publicado: (1979)

Critical examination of Ptbp1-mediated glia-to-neuron conversion in the mouse retina
por: Xie, Ye, et al.
Publicado: (2022)

SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 switching and RBFOX2 activity
por: Kim, Jung-Hyun, et al.
Publicado: (2021)

Ubiquitin Ligases CBL and CBL-B Maintain the Homeostasis and Immune Quiescence of Dendritic Cells
por: Tong, Haijun, et al.
Publicado: (2021)

Saikosaponin D: review on the antitumour effects, toxicity and pharmacokinetics
por: Zhou, Piao, et al.
Publicado: (2021)

Natural killer cells in antitumour adoptive cell immunotherapy
por: Laskowski, Tamara J., et al.
Publicado: (2022)

PTBP3 promotes tumorigenesis of glioblastoma by stabilizing Twist1
por: Xie, Peng, et al.
Publicado: (2022)

DNA Methyltransferase Inhibitors: Catalysts For Antitumour Immune Responses
por: Dan, Huimin, et al.
Publicado: (2019)

Bicarbonate transport as regulator of antitumour immunity in pancreatic cancer
por: Kay, Emily J., et al.
Publicado: (2023)

Features of peritoneal dendritic cells in the development of endometriosis
por: Qiaomei, Zheng, et al.
Publicado: (2023)

The PTBP1‑NCOA4 axis promotes ferroptosis in liver cancer cells
por: Yang, Hao, et al.
Publicado: (2023)

Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1
por: Leclerc, Marine, et al.
Publicado: (2019)

Host dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity
por: Almeida, Rafael Ribeiro, et al.
Publicado: (2020)

PTBP1 is a Novel Poor Prognostic Factor for Glioma
por: Liu, Pan, et al.
Publicado: (2022)

Antitumour activity of peroxidases.
por: Everse, K. E., et al.
Publicado: (1985)

The antitumour activities of statins
por: Takahashi, H.K., et al.
Publicado: (2007)

The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity
por: Xiao, Yichuan, et al.
Publicado: (2017)

PTBP1 Is Required for Embryonic Development before Gastrulation
por: Suckale, Jakob, et al.
Publicado: (2011)

PTBP1 mRNA isoforms and regulation of their translation
por: Arake de Tacca, Luisa M., et al.
Publicado: (2019)

Sodium Homeostasis, a Balance Necessary for Life
por: Bernal, Antonio, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0kcqma5hcd4869joaq60d3r30f