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Single-Cell Sequencing Reveals the Transcriptome and TCR Characteristics of pTregs and in vitro Expanded iTregs

Regulatory T cells (Tregs) play a critical role in the maintenance of immune tolerance and tumor evasion. However, the relative low proportion of these cells in peripheral blood and tissues has hindered many studies. We sought to establish a rapamycin-based in vitro Treg expansion procedure in patie...

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Detalles Bibliográficos
Autores principales: Hui, Zhenzhen, Zhang, Jiali, Zheng, Yu, Yang, Lili, Yu, Wenwen, An, Yang, Wei, Feng, Ren, Xiubao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044526/
https://www.ncbi.nlm.nih.gov/pubmed/33868236
http://dx.doi.org/10.3389/fimmu.2021.619932

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