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Application of high-throughput 5′P sequencing for the study of co-translational mRNA decay

mRNA degradation is connected to the translation process up to the degree that 5′-3′ mRNA degradation follows the last translating ribosome. To study 5′-3′co-translational mRNA decay and the associated ribosome dynamics, here we present an improved high-throughput 5′P degradome RNA sequencing protoc...

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Detalles Bibliográficos
Autores principales: Zhang, Yujie, Pelechano, Vicent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044721/
https://www.ncbi.nlm.nih.gov/pubmed/33870233
http://dx.doi.org/10.1016/j.xpro.2021.100447