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Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma

Glioma is the most common intracranial malignant tumor, and its specific pathogenesis has been unclear, which has always been an unresolved clinical problem due to the limited therapeutic window of glioma. As we all know, surgical resection, chemotherapy, and radiotherapy are the main treatment meth...

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Autores principales: Xie, Yandong, Han, Yuhan, Zhang, Xuefeng, Ma, Hongwei, Li, Linfeng, Yu, Rutong, Liu, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044949/
https://www.ncbi.nlm.nih.gov/pubmed/33869019
http://dx.doi.org/10.3389/fonc.2021.633827
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author Xie, Yandong
Han, Yuhan
Zhang, Xuefeng
Ma, Hongwei
Li, Linfeng
Yu, Rutong
Liu, Hongmei
author_facet Xie, Yandong
Han, Yuhan
Zhang, Xuefeng
Ma, Hongwei
Li, Linfeng
Yu, Rutong
Liu, Hongmei
author_sort Xie, Yandong
collection PubMed
description Glioma is the most common intracranial malignant tumor, and its specific pathogenesis has been unclear, which has always been an unresolved clinical problem due to the limited therapeutic window of glioma. As we all know, surgical resection, chemotherapy, and radiotherapy are the main treatment methods for glioma. With the development of clinical trials and traditional treatment techniques, radiotherapy for glioma has increasingly exposed defects in the treatment effect. In order to improve the bottleneck of radiotherapy for glioma, people have done a lot of work; among this, nano-radiosensitizers have offered a novel and potential treatment method. Compared with conventional radiotherapy, nanotechnology can overcome the blood–brain barrier and improve the sensitivity of glioma to radiotherapy. This paper focuses on the research progress of nano-radiosensitizers in radiotherapy for glioma.
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spelling pubmed-80449492021-04-15 Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma Xie, Yandong Han, Yuhan Zhang, Xuefeng Ma, Hongwei Li, Linfeng Yu, Rutong Liu, Hongmei Front Oncol Oncology Glioma is the most common intracranial malignant tumor, and its specific pathogenesis has been unclear, which has always been an unresolved clinical problem due to the limited therapeutic window of glioma. As we all know, surgical resection, chemotherapy, and radiotherapy are the main treatment methods for glioma. With the development of clinical trials and traditional treatment techniques, radiotherapy for glioma has increasingly exposed defects in the treatment effect. In order to improve the bottleneck of radiotherapy for glioma, people have done a lot of work; among this, nano-radiosensitizers have offered a novel and potential treatment method. Compared with conventional radiotherapy, nanotechnology can overcome the blood–brain barrier and improve the sensitivity of glioma to radiotherapy. This paper focuses on the research progress of nano-radiosensitizers in radiotherapy for glioma. Frontiers Media S.A. 2021-03-22 /pmc/articles/PMC8044949/ /pubmed/33869019 http://dx.doi.org/10.3389/fonc.2021.633827 Text en Copyright © 2021 Xie, Han, Zhang, Ma, Li, Yu and Liu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Xie, Yandong
Han, Yuhan
Zhang, Xuefeng
Ma, Hongwei
Li, Linfeng
Yu, Rutong
Liu, Hongmei
Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title_full Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title_fullStr Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title_full_unstemmed Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title_short Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title_sort application of new radiosensitizer based on nano-biotechnology in the treatment of glioma
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8044949/
https://www.ncbi.nlm.nih.gov/pubmed/33869019
http://dx.doi.org/10.3389/fonc.2021.633827
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